Developmemnt of high precision dose calculation system using Quantitative Susceptibility Mapping

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K19198
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Medical Physics and Radiological Technology
• Research Institution: Tohoku University
• Principal Investigator: Ito Kengo 東北大学, 大学病院, 助手 (40705076)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 定量的磁化率マッピング / MRI-based RTP / MRI-Linac

Outline of Final Research Achievements

Accurate evaluation of the relative electron density (rED) from MRI will enable treatment planning based on MR images alone. The aim of this study was to develop radiotherapy treatment planning method using magnetic susceptibility obtained from Quantitative Susceptibility Mapping (QSM) via MR imaging. This study demonstrates the feasibility of the method for generating an MRI substitute for a CT images. A correlation between magnetic susceptibility and rED was not observed using our proposed method. In contrast to the magnetic susceptibility values obtained from the QSM algorithm, which were strongly affected by calcification and iron content, the rED was not considerably affected by such materials.

Free Research Field

放射線治療