2016 Fiscal Year Final Research Report
A new trial design to develop early diagnosis medicine in psychiatry
| Project/Area Number |
15K19223
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Epidemiology and preventive medicine
|
|---|
| Research Institution | Aichi Medical University |
|---|
Principal Investigator |
|
|---|
| Research Collaborator |
KOTORII Nozomu
|
|---|
| Project Period (FY) |
2015-04-01 – 2017-03-31
|
| Keywords | 診断法の比較 / 臨床試験デザイン / 混合分布 / 多項分布 / 確定診断 |
|---|
| Outline of Final Research Achievements |
The development of diagnostic methods utilizing biomarkers to diagnose whether patients have certain diseases has been continuing. To date, the evaluation of such diagnostic methods has only been performed in patients who have received a 100% positive diagnosis (definitive diagnosis) of a certain disease. However, the process to reach a definitive diagnosis requires much time, thus there are difficulties in using this approach in patients who present with some psychiatric disorders for which it is difficult to make a definitive diagnosis. The applicant has discussed performance evaluations of diagnostic methods in cases where a definitive diagnosis is not possible in a previous study and obtained certain results (Murotani et al 2015). I develop a hybrid performance evaluation that utilizes the method by Murotani et al. 2015 and traditional methods.
|
| Free Research Field |
生物統計学
|
