Endoscopic ultrasound-guided through-the-needle-biopsy for the diagnosis of pancreatic cystic neoplasms

2016 Fiscal Year Final Research Report

• Project/Area Number: 15K19301
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Gastroenterology
• Research Institution: Hokkaido University
• Principal Investigator: Kawakubo Kazumichi 北海道大学, 医学研究科, 助教 (80633578)
• Research Collaborator: MITSUHASHI Tomoko 北海道大学病院, 病理診断部/病理部, 准教授 ; MIZUKAMI Yusuke 旭川医科大学, 内科学講座・消化器/血液腫瘍制御内科学分野, 准教授 ; ONO Yusuke 札幌東徳洲会病院, 付属臨床研究センター・臨床生体情報解析部 ; KUWATANI Masaki 北海道大学病院, 光学医療診療部, 助教
• Project Period (FY): 2015-04-01 – 2017-03-31
• Keywords: 膵嚢胞性腫瘍

Outline of Final Research Achievements

Endoscopic ultrasonography-guided through-the-needle cyst wall biopsy (EUS-TNCB) was performed in two patients. A 71-year-old female had 32mm cystic lesion in the head of the pancreas. EUS-TNCB revealed fragmented epithelial cells with small nucleus with interstitial fibrotic tissue. A 48-year-old male had 20mm cystic lesion in the body of the pancreas. EUS-TNCB revealed no epithelial cells but interstitial fibrotic tissue. Gene mutation analysis by next-generation sequencer could not detect any mutation in both samples.

Free Research Field

膵嚢胞性腫瘍