2016 Fiscal Year Final Research Report
Impact of a specific gut microbiota change on acute kidney injury mice
| Project/Area Number |
15K19450
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Kidney internal medicine
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| Research Institution | Kanazawa University |
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Principal Investigator |
Nakade Yusuke 金沢大学, 附属病院, 臨床検査技師 (10749360)
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Keywords | 腸内細菌 / 腎臓病 / バイオマーカー |
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| Outline of Final Research Achievements |
The aim of this study was to reveal the relationship between gut microbiota and kidney disease and to identify new biomarkers for kidney diseases. The contribution of gut microbiota to various disorders has been reported in recent years. However, the association of gut microbiota with kidney disease remains to be investigated. We revealed the alteration of gut bacteria in acute kidney injury mice with 16S rRNA analysis. This result raise the possibility that gut bacteria could be a new candidate of biomarkers for acute kidney injury. A patent has been applied for the biomarker of kidney injury according to our results.
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| Free Research Field |
臨床検査医学
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