2016 Fiscal Year Final Research Report
Criteria of tonsillectomy in IgA nephropathy
| Project/Area Number |
15K19468
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Kidney internal medicine
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| Research Institution | Juntendo University |
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Principal Investigator |
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| Research Collaborator |
SUZUKI Yusuke 順天堂大学, 医学部, 教授 (70372935)
SUZUKI Hitoshi 順天堂大学, 医学部, 准教授 (10468572)
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Keywords | IgA腎症 / 糖鎖異常IgA1 / 糖鎖異常IgA1特異的抗体 / 免疫複合体 / TLR9 / 扁桃 |
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| Outline of Final Research Achievements |
Serum levels of galactose-deficient IgA1 (Gd-IgA1) and Gd-IgA1-containing immune complexes are important for the pathogenesis of IgA nephropathy. Our observations suggested that a panel of serum biomarkers may be helpful in differentiating IgAN from other glomerular diseases. The biomarkers of tonsillar cells supernatant might be useful for criteria of tonsillectomy in IgA nephropathy.
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| Free Research Field |
腎臓
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