2017 Fiscal Year Final Research Report
Impact of diabetes mellitus on peripheral artery disease
| Project/Area Number |
15K19515
|
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| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
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| Research Field |
Metabolomics
|
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| Research Institution | Osaka University |
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Principal Investigator |
|
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| Project Period (FY) |
2015-04-01 – 2018-03-31
|
| Keywords | 末梢動脈疾患 / 糖尿病 |
|---|
| Outline of Final Research Achievements |
The impact of diabetes on prognosis in patients with peripheral artery disease and the risk of peripheral artery disease in diabetic patients were investigated. In patients with peripheral artery disease, diabetes was associated with major amputation. In cases with critical limb ischemia, diabetes was associated with blow-the-knee lesion and arterial calcification, as well as an increased risk of major adverse limb events after endovascular therapy. Diabetes had a potential to influence the association of revascularization strategies and clinical outcomes. In diabetic patients, peripheral neuropathy was not directly correlated with peripheral artery disease. The assessment of borderline anke-brachial index was associated with improved diagnostic accuracy of peripheral artery disease.
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| Free Research Field |
糖尿病
|
