2016 Fiscal Year Final Research Report
Elucidation of involvement in tumorigenesis and clinical significance of CD25 expression in hematopoietic tumors
| Project/Area Number |
15K19556
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Hematology
|
|---|
| Research Institution | Jichi Medical University |
|---|
Principal Investigator |
|
|---|
| Research Collaborator |
Muroi Kazuo 自治医科大学, 医学部, 教授 (50190939)
|
|---|
| Project Period (FY) |
2015-04-01 – 2017-03-31
|
| Keywords | CD25 / soluble IL-2 receptor / lymphoma |
|---|
| Outline of Final Research Achievements |
CD25 positive acute myeloid leukemia (AML) was associated with poor prognosis after stem cell transplantation. CD25 expression was an independent risk factor for complete remission and event free survival in elderly AML. High level of pretreatment soluble CD25 was an independent prognostic factor for transformation in follicular lymphoma (FL). Measure of pretreatment and posttreatment soluble CD25 was useful to predict the prognosis of FL.
|
| Free Research Field |
血液
|
