2017 Fiscal Year Final Research Report
Lithium for mild-to-moderate Alzheimer's disease: A randomized double-blind, placebo-controlled study
| Project/Area Number |
15K19750
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Psychiatric science
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| Research Institution | Fujita Health University |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | アルツハイマー型認知症 / リチウム / ランダム化比較試験 |
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| Outline of Final Research Achievements |
Previous studies suggest that lithium inhibits the progression of cognitive dysfunction of Alzheimer disease. In 2015, we conducted a systematic review and a meta-analysis of randomized controlled trials and reported that lithium may have the effect of inhibiting the progress of cognitive dysfunction on Alzheimer disease. Based on these results, we started a double-blind, placebo-controlled, randomized controlled trial on the efficacy and safety of lithium on Alzheimer disease for Japanese population. Currently, this trial is recruiting subjects.
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| Free Research Field |
老年精神医学
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