2016 Fiscal Year Final Research Report
The relation between hepatic fiblosis and liver metastasis
Project/Area Number |
15K19910
|
Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Digestive surgery
|
Research Institution | Keio University |
Principal Investigator |
Kondo Takayuki 慶應義塾大学, 医学部(信濃町), 助教 (40626701)
|
Project Period (FY) |
2015-04-01 – 2017-03-31
|
Keywords | 肝転移 / 肝線維化 / 大腸癌 |
Outline of Final Research Achievements |
In spleen injection, the number of liver metastasis in NASH group is higher than in normal liver group. In anti-Ki67 antibody in Immunohistochemistry, the number of stained nuclear in liver metastasis foci in NASH group was higher than in normal liver group. The ability of proliferation in Nash group was higher than in normal liver group. The ability of migration and invasion of colon cancer cell line was elevated in co-cultured with IL-13. The ability of proliferation was elevated in a concentration dependent fashion.
|
Free Research Field |
消化器
|