2016 Fiscal Year Final Research Report
Identification of HOTAIR as a target of lung cancer
Project/Area Number |
15K19946
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Respiratory surgery
|
Research Institution | Miyagi Prefectural Hospital Organization Miyagi Cancer Center |
Principal Investigator |
Nakagawa Takayuki 地方独立行政法人宮城県立病院機構宮城県立がんセンター(研究所), がん幹細胞研究部, 特任研究員 (10626261)
|
Project Period (FY) |
2015-04-01 – 2017-03-31
|
Keywords | 肺癌 |
Outline of Final Research Achievements |
The aim of this study is to elucidate the molecluar mechanisms of lung cancer development and the identification of cancer stem cell-related genes. Our study demonstrated that some chemokines were identified as downstream molecules of HOTAIR. These data suggested that HOTAIR-chemokine axis contribute to the development of lung cancer.
|
Free Research Field |
呼吸器病態学
|