2016 Fiscal Year Final Research Report
Research for the identification of the genetic factor for ischemic stroke
| Project/Area Number |
15K19949
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Neurosurgery
|
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| Research Institution | The University of Tokyo |
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Principal Investigator |
|
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| Project Period (FY) |
2015-04-01 – 2017-03-31
|
| Keywords | 脳梗塞 / 頭蓋内主幹動脈狭窄 / RNF213 / 動脈硬化 / negative remodeling / 全エクソン解析 |
|---|
| Outline of Final Research Achievements |
We have conducted a basic research aiming at the establishment of preventive medicine for ischemic stroke caused by intracranial major artery stenosis. We have collected DNA samples and clinical information from over 1200 patients with various cerebrovascular diseases. We have reported several clinical characteristics of the intracranial major artery stenosis with RNF213 c.14576G>A variant. We have performed comprehensive genetic analysis aiming at the identification of the novel genetic variant causative for the onset of ischemic stroke.
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| Free Research Field |
脳神経外科学
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