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2016 Fiscal Year Final Research Report

Role of histamine nervous system in inhaled anesthesia.

Research Project

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Project/Area Number 15K20028
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Anesthesiology
Research InstitutionTohoku Medical and Pharmaceutical University (2016)
Tohoku University (2015)

Principal Investigator

NAKAMURA Tadaho  東北医科薬科大学, 医学部, 准教授 (80734318)

Project Period (FY) 2015-04-01 – 2017-03-31
Keywords吸入麻酔薬 / 中枢神経系薬理 / ヒスタミン神経系
Outline of Final Research Achievements

In present study, we focused on the relation between inhaled anesthetics and histamine nervous system. We found that histamine H1 receptor was involved in loss of consciousness induced by inhaled anesthetics and histamine release from histamine neurons in posterior hypothalamus was facilitated by inhaled anesthetics.

Free Research Field

薬理学

URL: 

Published: 2018-03-22  

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