2017 Fiscal Year Final Research Report
Analysis of the mechanism for control of proliferation of ovarian and endometrial cancer stem cells
| Project/Area Number |
15K20132
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | Niigata University |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | がん幹細胞 / 子宮体がん / 卵巣がん |
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| Outline of Final Research Achievements |
We established and grew spheroid cell cultures from a variety of endometrial and ovarian cancer specimens. Endometrial cancer spheroid cells that expressed the cancer stem cell specific marker X formed larger tumors and grew more rapidly than the cells that did not express marker X. These results demonstrate the importance of marker X in proliferation of endometrial cancer stem cells. All procedures were performed following protocols approved by the Ethics and Animal Care and Use Committees of Niigata University.
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| Free Research Field |
婦人科腫瘍
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