Development of photodynamic therapy for the allergic rhinitis

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K20182
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Otorhinolaryngology
• Research Institution: Chiba University
• Principal Investigator: SUZUKI TAKESHI 千葉大学, 大学院医学研究院, 助教 (20422230)
• Research Collaborator: OKAMOTO Yoshitaka 千葉大学, 大学院医学研究院, 教授 (40169157) ; SAKURAI Daijyu 千葉大学, 大学院医学研究院, 講師 (10375636) ; YONEKURA Syuji 千葉大学, 大学院医学研究院, 講師 (20400939) ; OKUMA Yusuke 千葉大学, 大学院医学研究院, 医員 (50745825) ; KUNII Naoki 千葉大学, 大学院医学研究院, 助教 (00456047) ; MORIMOTO Yuki 千葉大学, 大学院医学研究院, 医員 (40802575)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 光線力学的治療 / アミノレブリン酸 / アレルギー性鼻炎

Outline of Final Research Achievements

The aim of current study is development of photodynamic therapy for the allergic rhinitis. The photodynamic therapy was performed for two participants with allergic rhinitis. Nasal pains were reported in both cases. The total nasal symptom score (a 12-point scale with 4 categories from 0 to 3, as follows: 0, none and 3, severe; subjective symptom severity of sneezing, rhinorrhea, nasal congestion and itchy nose) decreased 28 days after photodynamic therapy from 4.7 to 1.0 (participant 1) and from 5.7 to 1.7.

Free Research Field

アレルギー性鼻炎