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2016 Fiscal Year Final Research Report

Characteristics and prevalence of uveitis in CIHHV-6 patients

Research Project

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Project/Area Number 15K20293
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Ophthalmology
Research InstitutionNara Medical University

Principal Investigator

Yoshikawa Tadanobu  奈良県立医科大学, 医学部, 助教 (20632764)

Project Period (FY) 2015-04-01 – 2017-03-31
Keywordsぶどう膜炎
Outline of Final Research Achievements

Multiplex PCR for herpes virus was performed in 27 eyes of 27 patients suspected herpes virus associated disease. The mean ± standard deviation age of the patients was 63.1±14.5 years. Of the 27 eyes, 12 eyes had iritis, 6 eyes had uveitis, 1 eye had endophthalmitis, 1 eye had cytomegalovirus retinopathy, 4 eyes had acute retinal necrosis, 2 eyes had secondary glaucoma, and 1 eye had herpetic keratitis. Multiplex PCR for herpes virus demonstrated that 4 eyes were cytomegalovirus positive, 2 eyes were herpes simplex virus-1 positive, 2 eyes were varicella zoster virus positive, 1 eye was Epstein-Barr virus positive, and 18 eyes were negative. None of the eyes had human herpes virus-6. Thus prevalence of uveitis with CIHHV-6 and characteristics of CIHHV-6 was unclear.

Free Research Field

眼科

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Published: 2018-03-22  

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