2017 Fiscal Year Final Research Report
The study of the new adhesive which combine MMPs activity inhibitor
| Project/Area Number |
15K20404
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Conservative dentistry
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| Research Institution | Kagoshima University (2016-2017)
Okayama University (2015) |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | 象牙質 / MMPs / 接着 |
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| Outline of Final Research Achievements |
In this study, I examined influence of the MMPs activity inhibitors on mechanical properties of the decalcified dentin and the experimental bonding system that combined the MMPs activity inhibitors with bonding resin of the self-etching system. 1). Influence on mechanical property: MMPs activity inhibitors treatment improved the mechanical property of the decalcified dentin. 2)．Influence in the dentin adhesion: In early adhesion examination, there were no decline of the bonding strength the combination to bonding agents with tannic acid until 1%. In 6 months storage, tannic acid controlled degradation of the bonding strength.
Because the change of color of the tooth substance with tannic acid and Saforide were accepted, the development of the MMPs activity inhibitors which does not cause a change of color is necessary.
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| Free Research Field |
歯科保存学
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