2017 Fiscal Year Final Research Report
New approach for bone regeneration using composite of osteoblast and Ar-PVDC film
| Project/Area Number |
15K20493
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Dental engineering/Regenerative dentistry
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| Research Institution | Aichi Gakuin University |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | 再生歯学 / 組織工学 |
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| Outline of Final Research Achievements |
The purpose of this study is to promote bone defect healing using composite of osteoblast and Ar-modified Polyvinylidene chloride (Ar-PVDC) film. First, the alkaline phosphatase (ALP) activity on Ar-PVDC was assessed for differentiation. The ALP activity of osteoblast was enhanced on Ar-PVDC than that of PVDC.
Next, composite of osteoblast and Ar-PVDC film was transplanted in bone defect of rat femur. However, there is no difference between Ar-PVDC and Ar-PVDC. This result suggest that the osteoconductivity of Ar-PVDC is high.
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| Free Research Field |
歯周治療学
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