2016 Fiscal Year Final Research Report
Novel thermo-chemotherapy for oral cancer using a new magnetic anti-cancer drug
| Project/Area Number |
15K20552
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Surgical dentistry
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| Research Institution | Yokohama City University |
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Principal Investigator |
SATO Itaru 横浜市立大学, 医学研究科, 客員研究員 (00737710)
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Keywords | 抗癌剤 / 温熱療法 |
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| Outline of Final Research Achievements |
Radical surgery for patients with head and neck cancer often causes major dysfunctions, such as dysphagia, dysarthria, or mastication disorder, leading to impaired quality of life. Here, a new magnetic anticancer drug has been developed. This drug has two characteristics; anti-cancer effect and hyperthermic effect in combination with an alternating current magnetic field (ACMF). We have evaluated the anti-cancer effects of a new magnetic anticancer drug using oral cancer cells in vitro.The results in this study demonstrated the unique property of the novel magnetic anticancer compound. In particular, this drug had anti-cancer effect with heat induction in an ACMF. This drug may thus be useful in a novel cancer therapy in the future.
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| Free Research Field |
口腔癌
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