2017 Fiscal Year Final Research Report
The construction of treatment system and establishment of diagnosis for dental psychosomatic disease by two-dimensional matrix formation
| Project/Area Number |
15K20651
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Social dentistry
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| Research Institution | The Nippon Dental University |
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Principal Investigator |
Kato Yuichi 日本歯科大学, 生命歯学部, 助教 (70720803)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | 歯科心身医学 / 口腔異常感症 / 非定型歯痛 |
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| Outline of Final Research Achievements |
We studied oral dysesthesia, which is one of the typical diseases of dental psychosomatic disorder. There are few reports that aripiprazole, an antipsychotic, is effective for dysesthesia. In this study, aripiprazole showed inhibitory action on dopamine, while knowledge was obtained on the effect of alleviation in the oral dysesthesia due to the characteristic that it has the intrinsic activity as an agonist.
These findings are a possibility to bring new knowledge that not only drugs acting on noradrenaline and GABA receptors but also drugs acting on dopamine are also effective as compared with the conventional thinking.
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| Free Research Field |
歯科心身医学
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