The assessment of the effectiveness and safety of seasonal influenza vaccine among Japanese pregnant women and children

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K20862
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Medical pharmacy; Epidemiology and preventive medicine
• Research Institution: Tohoku University
• Principal Investigator: OBARA Taku 東北大学, 大学病院, 准教授 (80612019)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 医薬品情報・安全性学

Outline of Final Research Achievements

In Japan, information on the effectiveness and safety of seasonal influenza vaccine among pregnant women and infants has not been available, differently from foreign countries. The aim of the present study was to evaluate the efficacy and safety of injection of influenza vaccine among pregnant women and infants in Japan based on the established study basements. In the babies' and their parents' longitudinal observation in Suzuki Memorial Hospital on intrauterine period (BOSHI) study and the Japan Environment and Children's Study (JECS), we completely collected the information on the injection of influenza vaccination among pregnant women and continued the follow-up survey for infants. We also clarified that the prevalence of infants who received influenza vaccine, that of infected by influenza virus, and had an experience of adverse drug reaction by influenza vaccination were not different between influenza seasons from 2015 to 2017.

Free Research Field

薬剤疫学