2016 Fiscal Year Final Research Report
Development of 3D-Magnetic Tweezer System for Live Cell Experiment
| Project/Area Number |
15K20994
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Intelligent mechanics/Mechanical systems
Biomedical engineering/Biomaterial science and engineering
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| Research Institution | Tokyo Institute of Technology |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Keywords | 非接触マニピュレーション / 磁気駆動 / 精密画像計測 / 設計工学 |
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| Outline of Final Research Achievements |
This research is aiming to figure out a systematic design procedure of sextuple 3D-magnetic tweezer that is utilizing magnetic levitation technique to achieve a non-contact magnetic force exertion to a micro-sized magnetic particle, which is effective for establishing a position control of a free-floating particle in medium or a measurement of mechanical property, such as stiffness, of a specimen cell on which the particle is attached. In order to satisfy a given specification which includes a strength, frequency and a size of workspace in which anisotropy of the generative force can be within a permissible value, a practical procedure to find a combination of proper material, tip shape and number of turns of excitation coils was determined. By using this procedure, a setup has been fabricated, and a semi-closed loop magnetic force control using a Hall element sensor mounted on each pole’s end side was applied. Obtained performance of the developed system was experimentally evaluated.
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| Free Research Field |
機構学，設計工学，磁気駆動，画像計測
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