Elucidation of immune condition in diabetic patients induced carcinogenic susceptibility

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K21022
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Epidemiology and preventive medicine; Gastroenterology
• Research Institution: Kanazawa University
• Principal Investigator: Takuya Komura 金沢大学, 医学系, 協力研究員 (90623322)
• Research Collaborator: Sakai Yoshio 金沢大学, 医学系, 准教授 (80401925)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 糖尿病 / 易発がん / 免疫状態

Outline of Final Research Achievements

We could establish a murine model of impaired glucose tolerance.
Next, We also could establish a murine model of pancreatic ductal adenocarcinoma model. We disclosed that frequency of myeloid derived suppressor cells was increased along increment of tumor size in this tumor bearing mice.

Free Research Field

腫瘍学