2017 Fiscal Year Final Research Report
Inactivation of antibiotic-resistant bacteria in sewage water treatment plant: Is the sewer system a pool of antibiotic-resistant genes?
| Project/Area Number |
15K21596
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Civil and environmental engineering
Environmental engineering and reduction of environmental burden
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| Research Institution | Kitasato University (2017)
Oita National College of Technology (2015-2016) |
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Principal Investigator |
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| Research Collaborator |
Sei Kazunari
Konishi Tadashi
Mekata Tohru
Hashimoto Reina
Jikumaru Atsushi
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | 薬剤耐性菌 / 薬剤耐性遺伝子 / 下水処理場 / バンコマイシン / バンコマイシン耐性遺伝子 / 従属栄養細菌 |
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| Outline of Final Research Achievements |
To clarify the behavior of antibiotic-resistant bacteria (ARB) and antibiotic-resistant genes (ARGs) in sewage water treatment plant, the presence of heterotrophic bacteria resistant to vancomycin and vanA and vanB, vancomycin resistant genes in each sewage water and sludge sample were determined. Heterotrophic bacteria resistant to vancomycin and vanA and vanB were detected from all sewage water and sludge samples even in the chlorinated water. Furthermore, in batch-type chlorination experiment of vancomycin-resistant enterococci (VRE) were carried out. Although VRE could be inactivated completely by chlorination, vanA gene could not be destroyed and remained in chlorinated water. Our results strongly indicated that sewage water treatment plant might play as pools of ARB and ARGs and discharge to water environments.
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| Free Research Field |
水環境工学
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