Analysis and prediction of the dynamics of Polycyclic aromatic hydrocarbons in the coastal environment polluted by heavy oil.

2006 Fiscal Year Final Research Report Summary

• Project/Area Number: 16310006
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Environmental dynamic analysis
• Research Institution: Kanazawa University
• Principal Investigator: KAWANISHI Takuya Graduate School of Natural Science and Technology, Associate Professor, 自然科学研究科, 助教授 (80234087)
• Co-Investigator(Kenkyū-buntansha): HAYASHI Yoshishige Graduate School of Natural Science and Technology, Professor, 自然科学研究科, 教授 (60019750) ; SATO Tsutomu Graduate School of Engineering, Hokkaido University, Associate Professor, 大学院・工学研究科, 助教授 (10313636) ; KAMATA Naoto Graduate School of Agricultural and Life Sciences, University of Tokyo, Associate Professor, 大学院・農学生命科学研究科, 助教授 (90303255) ; TAZAKI Kazue Graduate School of Natural Science and Technology, Professor, 自然科学研究科, 教授 (80211358) ; HAYAKAWA Kazuichi Graduate School of Natural Science and Technology, Professor, 自然科学研究科, 教授 (40115267)
• Project Period (FY): 2004 – 2006
• Keywords: Environmental changes / Environmental analysis / Environmental Technology / Dynamics of chemical substances / Partition coefficients / Mouth of rivers / Transport / Model

Research Abstract

The concentration of polycyclic aromatic hydrocarbons (PAHs) in the coastal sands and other media of a heavily polluted site of the Nakhodka oil spill were found to be as low as the background after the 7 years of the accident. Oil residues were found only in the hollows and cavities of the rocks, and PAH contents in those residues decreased to one thirds of the original value in two years, but after that, PAHs contents remained at the same level, suggesting that PAHs will remain long as oil residues.
Two years of monitoring of PAHs in the river water, SS and sediments revealed that the main sorbent of the PAHs in the sediments was organic matter. Organic matter based partition coefficient Koc was found to be well correlated to octanol-water partition coeffient, and can be described by using liner free-energy assumption.
The exchange of PAHs between surface sediments and river water was sufficiently fast for allowing us to consider that the partition between the sediments and water is approximately in equilibrium.
In the laboratory experiments, we investigated the effect of dissolved organic matter (DOM) on the partition of PAHs between sediments and water, and found that as the number of aromatic rings increases, the effect of DOM increases, and also found that for the precise description of the phenomena, we have to take into account the adsorption of DOM to the sediment particles.
As described above, in the coastal environment, exchange between water and coastal particulate media is sufficiently fast to remove the pollutants from the polluted sites in several years, and at the mouth of the river, that is so fast that we can assume an approximate equilibrium. Sorption of PAHs to particulate matter is mainly to organic matter, and the partition coefficient is larger as the number of aromatic rings increases, and can be roughly estimated by using linear free energy assumptions.

Research Products

• [Journal Article] Long-range transport of polycyclic aromatic hydrocarbons (PAHs) from the eastern Asian continent to Kanazawa, Japan with Asian dust Atmospheric Environment. (2007)
  • Author(s): Tamamura, S., Sato, T., Ota, Y., Wang, X., Tang N., Hayakawa, K.
  • Journal Title: Atmos. Environ. 41 Pages: 2580-2593
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Study on atmospheric polycyclic aromatic hydrocarbons at a background site of Ishikawa prefecture. Japan. (2007)
  • Author(s): Yang, X.-Y., Okada, Y., Tang, N., Toriba, A., Hayakawa K.
  • Journal Title: J. Ecotech. Research 13 Pages: 5-9
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] 中国吉林省延辺州における地下水及び河川水の窒素濃度と負荷解析 (2007)
  • Author(s): 鄭英杰, 川西琢也ほか
  • Journal Title: Journal of Ecotechnology Research 13・1 Pages: 43-52
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] 多環芳香族炭化水素及びニトロ多環芳香族炭化水素から見た中国東北地方の大気環境. (2007)
  • Author(s): 唐 寧, 田村憲治, 楊 小陽, 亀田貴之, 鳥羽 陽, 早川和一
  • Journal Title: J. Ecotech. Res. 13 Pages: 35-42
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Profiles of Particulate-Bound Polycyclic Aromatic Hydrocarbons and Their Nitrated Derivatives in Three Typical Cities, Liaoning Province, China. (2007)
  • Author(s): Hattori, T., Tang, N., Tamura, K., Hokoda, A., Yang, X.-Y., Igarash K., Ohno, M., Okada, Y., Toriba, A., Hayakawa, K.
  • Journal Title: Environ. Forensics 8 Pages: 165-172
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Rapid and sensitive determination of tryptophan, serotonin and psychoactive tryptamines by thin-layer chromatography/fluorescence detection. (2007)
  • Author(s): Kato, N., Kojima, T., Yoshiyagawa, S., Ohta, H., Toriba, A., Nishimura, H., Hayakawa K.
  • Journal Title: J. Chromatogr. A 1145 Pages: 229-233
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Development of analytical methods for polycyclic aromatic hydrocarbon compounds (PAHs) in airborne particulates : A review. (2007)
  • Author(s): Liu, Li-bin, Liu, Yan, Lin, J.-M., Tang, N, Hayakawa, K., Meda, T.
  • Journal Title: J. Envirn. Sci. 19 Pages: 1-11
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Long-range transportation o polycyclic aromatic hydrocarbons (PAHs) from the eastern Asian continent to Kanazawa, Japan with Asian dust. (2007)
  • Author(s): Tamamura, S., Sato, T., Ota, Y., Wang, X., Tang, N.Hayakawa, K.
  • Journal Title: Atmos. Environ. 41 Pages: 2580-2593
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Investigation of the Nitrogen Concentration in Groundwater and River Water and Nitrogen Loads to the Environment in Yanbian, Jilin, China. (2007)
  • Author(s): Zheng, Y., Hayashi, Y., Jin, D., Piao, C., Liu F., Kawashima H., Shindo J., Okamoto K., Kawanishi, T.
  • Journal Title: Journal of Ecotechnology Research 13(1) Pages: 43-52
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Atmosperic environment in the northwest region of China in view of polycyclic aromatic hydrocarbons and nitroplycyclic aromatic hydrocarbons. (2007)
  • Author(s): Ning, T., Tamura, K., Yan, X., Kameda, T., Toriba, A., Hayakawa, K.
  • Journal Title: J. Ecotech. Res. 13 (1) Pages: 35-42
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Profiles of Particulate-Bound (2007)
  • Author(s): Hattori, T., Tang, N., Tamura, K., Hokoda, A., Yang, X.-Y, Igarash K., Ohno, M., Okada, Y, Toriba, A., Hayakawa, K.
  • Journal Title: Environ. Forensics 8 (1 ＆ 2) Pages: 165-172
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Rapid and sensitive determination of tryptophan, serotonin and psychoactive tryptamines by thin-layer chromatography/fluorescence detection. (2007)
  • Author(s): Kato, N., Kojima, T., Yoshiyagawa, S., Ohta, H., Toriba, A., Nishimura, H., Hayakawa K.
  • Journal Title: J. Chromatogr. A 1145 (1-2) Pages: 229-233
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Development of analytical methods for polycyclic aromatic hydrocarbon compounds (PAHs) in airborne particulates : A review. (2007)
  • Author(s): Liu, L-B., Liu, Y., Lin, J.-M., Tang, N., Hayakawa, K., Meda, T.
  • Journal Title: J. Envim. Sci. 19 Pages: 1-11
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Damage to and recovery of coastlines polluted with C-heavy oil spilled from Nakhodka. (2006)
  • Author(s): Hayakawa, K., Kawanishi, T., Toriba, A., Kizu, R., Tamiya, E., et al.
  • Journal Title: Water Res 40・5 Pages: 981-989
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Competitive Sorption of Pyrene on Wood Chars. (2006)
  • Author(s): Wang, X., Sato, T., Xing, B.
  • Journal Title: Environ. Sci. Technol. 40 Pages: 3267-3272
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Decomposition of polycyclic aromatic hydrocarbon (PAHs) on mineral surface under controlled relative humidity. (2006)
  • Author(s): Tamamura, S., Sato, T., Ota, Y., Tang, N., Hayakawa, K.
  • Journal Title: Acta Geologica Sinica 80 Pages: 185-191
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Litter and Soil Carbon Dynamics Model in Arid Forest Ecosystems : Application to Sturt Meadows Experiments in Western Australia. (2006)
  • Author(s): Kumada, S., Kawanishi, T.et al.
  • Journal Title: Journal of Ecotechnology Research 12・3 Pages: 167-170
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Occurrence of polybrominated diphenyl ethers and polychlorinated biphenyls in shark liver oil supplements. (2006)
  • Author(s): Akutsu, K., Tanaka, Y., Hayakawa, K.
  • Journal Title: Food Addit. Contam. 23 Pages: 1323-1329
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Simultaneous determination of urinary hydroxylated metabolites of naphthalene, fluorine, phenanthrene, fluoranthene and pyrene as multiple biomarkers of exposure to polycyclic aromatic hydrocarbons. (2006)
  • Author(s): Chetiyanukornkul, T., Toriba, A., Kameda, T., Tang, N., Hayakawa, K.
  • Journal Title: Anal. Bioanal. Chem. 386 Pages: 712-718
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Atmospheric Deposition of Polychlorinated Dibenzo-p-dioxins (PCDDs) and Polyclorinated Dibenzofurans (PCDFs) in Kanazawa, Japan. (2006)
  • Author(s): Oka, H., Kakimoto, H., Miyata, Y., Yonezawa, Y., Niikawa, A., Kyudoh, H., Kizu, R., Hayakawa, K.
  • Journal Title: J. Health Sci. 52 Pages: 300-307
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Homologue and Isomer Distribution of Dioxins Observed in Water Samples Collected from Kahokugata Lagoon and Inflowing Rivers, Japan. (2006)
  • Author(s): Kakimoto, H., Oka, H., Miyata, Y., Yonezawa, Y., Niikawa, A., Kyodo, H., Tang, N., Toriba, A., Kizu, R., Hayakawa, K.
  • Journal Title: Water Res. 40 Pages: 1929-1940
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Seasonal Change of Gas/Particle Partitioning of Atmospheric Dioxins. (2006)
  • Author(s): Oka, H., Kakimoto, H., Miyata, Y., Yonezawa, Y., Niikawa, A., Kyudoh, H., Tang, N., ToribaA., Kizu, R., Hayakawa, K.
  • Journal Title: J Health Sci. 52 Pages: 50-57
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Determination of 1-nitropyrene metabolites by high performance liquid chromatography with chemiluminescence detection. (2006)
  • Author(s): Hayakawa, K., Lu, C., Mizukami, S., Toriba, A., Tang, N.
  • Journal Title: J. Chromatogr. A 1107 Pages: 286-289
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Distribution and Characterization of Polycyclic Aromatic Hydrocarbon Compounds in Airborne Aarticulates of East Asia (2006)
  • Author(s): Liu, Yan, Liu, Li-bin, Lin, J.-M., Tang, N., Hayakawa, K.
  • Journal Title: China Perticuology 4 Pages: 283-292
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] 大気中の多環芳香族炭化水素類の計測法とその発生・動態解析研究の進歩 (2006)
  • Author(s): 亀田貴之, 早川和一
  • Journal Title: 自動車研究 28 Pages: 653-657
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Comparison of traditional cloud-point extraction and on-line flow-injection cloud-point extraction with a chemiluminescence method using benzo[α]pyrene as a marker. (2006)
  • Author(s): Song, G.-Q., Lu, C., Hayakawa, K., Lin, J.-M.
  • Journal Title: Anal. Bioanal. Chem. 384 Pages: 1007-1012
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Damage to and recovery of coastlines polluted with C-heavy oil spilled from Nakhodka. (2006)
  • Author(s): Hayakawa, K., Nomura, M., Nakagawa, T., Oguri, S., Kawanishi, T., Toriba, A., Kizu, R., Sakaguchi, T., Tamiya, E.
  • Journal Title: Water Research 40 (5) Pages: 981-989
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] (2006) Competitive Sorption of Pyrene on Wood Chars. (2006)
  • Author(s): Wang, X., Sato, T., Xing, B.
  • Journal Title: Environ. Sci. Technol. 40 Pages: 3267-3272
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Decomposition of polycyclic aromatic hydrocarbon (PAHs) on mineral surface under controlled relative humidity. (2006)
  • Author(s): Tamamura, S., Sato, T., Ota, Y, Tang, N., Hayakawa, K.
  • Journal Title: Acta Geologica Sinica 80 Pages: 185-191
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Litter and Soil Carbon Dynamics Model in Arid Forest Ecosystems : Application to Sturt Meadows Experiments in Western Australia. (2006)
  • Author(s): Kumada, S., Kawanishi, T., Hayashi, Y, Ogomori, K., Kobayashi, Y., Takahashi, N., Saito, M., Hamano, H., Kojima T., Yamada, K.
  • Journal Title: Journal of Ecotechnology Research 12(3) Pages: 167-170
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Occurrence of polybrominated diphenyl ethers and polychlorinated biphenyls in shark liver oil supplements (2006)
  • Author(s): Akutsu, K., Tanaka, Y., Hayakawa, Y
  • Journal Title: Food Addit. Contam. 23 (12) Pages: 1323-1329
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Simultaneous determination of urinary hydrxylated metabolites of naphthalene, fluorine, phenanthrene, fluoranthene and pyrene as multiple biomarkers of exposure to polycyclic aromatic hydrocarbons. (2006)
  • Author(s): Chetiyanukornkul, T., Toriba, A., Kameda, T., Tang, N., Hayakawa, K.
  • Journal Title: Anal. Bioanal. Chem. 386 Pages: 712-718
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] O, Atmospheric Deposition of Polychlorinated Dibenzo-β-dioxins (PCDDs) and Polyclorinated Dibenzofurans (PCDFs) in Kanazawa, Japan. (2006)
  • Author(s): ka, H., Kakimoto, H., Miyata, Y, Yonezawa, Y, Niikawa, A., Kyudoh, H., Kizu, R., Hayakawa, K.
  • Journal Title: J. Health Sci. 52 (3) Pages: 300-307
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Homologue and isomer distribution of dioxins observed in water samples collected from Kahokugata Lagoon and inflowing rivers, Japan. (2006)
  • Author(s): Kakimoto, H., Oka, H., Miyata, Y, Yonezawa, Y, Niikawa, A., Kyudo, H., Tang, N., Toriba, A., Kizu, R., Hayakawa, K.
  • Journal Title: Water Res. 40(10) Pages: 1929-1940
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Seasonal Change of Gas/Particle Partitioning of Atmospheric Dioxins. (2006)
  • Author(s): Oka, H., Kakimoto, H., Miyata, Y, Yonezawa, Y, Niikawa, A., Kyudoh, H., Tang, N., Toriba A., Kizu, R., Hayakawa, K.
  • Journal Title: J Health Sci. 52 (1) Pages: 50-57
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Distribution and Characterization of Polycyclic Aromatic Hydrocarbon Compounds in Airborne Particulates of East Asia. (2006)
  • Author(s): Liu, Y., Liu, L., Lin, J-M., Tang, N., Hayakawa, K.
  • Journal Title: China Particuology 4 (6) Pages: 283-292
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Comparison of traditional cloud-point extraction and on-line flow-injection cloud-point extraction with a chemiluminescence method using benzo[a]pyrene as a marler. (2006)
  • Author(s): Song, Q.G., Lu, C., Hayakawa, K., Lin, J-M.
  • Journal Title: Anal. Bioanal. Chem. 384 Pages: 1007-1012
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Recent studies on polycyclic aromatic hydrocarbons : Analytical methods and formation, environmental behaviors. Books (2006)
  • Author(s): Kameda T.amd Hayakawa K.
  • Journal Title: Jidousha Kenkyuu 28 Pages: 653-657
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] The behavior of polycycloic aromatic hydrocarbons in an aquatic environment in the Hokuriku region, Past, Present and Future Environments of Pan-Japan Sea Region (Hayakawa, K. et al. eds.) (2006)
  • Author(s): Kawanishi, T., Van D.A., Sano, Y., Hayashi, Y.
  • Journal Title: Maruzen Co. Ltd. Pages: 353-364
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Enhanced activity and stability of Chromobacterium visocosum lipase in AOT reverse micellar systems by pretreatment with acetone. (2005)
  • Author(s): Zaman, M.M., Hayashi, Y., Talukder, M.M.R., Kawanishi, T.
  • Journal Title: Journal of Molecular Catalysis B : Enzymatic 32 Pages: 149-155
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Pretreatment of Chromobacterium viscosum lipase with acetone increases its activity in sodium bis-(2-ethylhexyl) sulfosuccinate (AOT) reverse micelles. (2005)
  • Author(s): Talukder, M.M.R., Zaman, M.M., Hayashi, Y., Wu, J.C., Kawanishi.T.
  • Journal Title: Journal of Chemical Technology and Biotechnology 80(10) Pages: 1166-1169
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Enhanced activity and stability o Chromobacterium visocosum lipase in AOT reverse micellar systems by pretreatment with acetone. (2005)
  • Author(s): Zaman, M.M., Hayashi, Y., Talukder, M.M.R.Kawanishi, T.
  • Journal Title: Journal of Molecular Catalysis B : Enzymatic 32 (4) Pages: 149-155
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Pretreatment of Chromobacterium viscosum lipase with acetone increases its activity in sodium bis-(2-ethylhexyl) sulfosuccinate (AOT) reverse micelles (2005)
  • Author(s): Talukder, M.M.R., Zaman, M.M., Hayashi, Y., Wu, J.C.Kawanishi, T.
  • Journal Title: Journal of Chemical Technology and Biotechnology 80 (10) Pages: 1166-1169
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] (wrote a part of the book) in the Japan Society of Energy (Ed.) Energy and Environment Keyword dictionary (2005)
  • Author(s): Takuya Kawanishi T.
  • Journal Title: Corona Publishing Pages: Co.-480
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] A Determination Method for Nitrocatecholamines in Rat Brain with High-Performance Liquid Chromatography-Peroxyoxalate Chemiluminescence Detection.
  • Author(s): Tsunoda, M., Uchino, E., Imai, K., Hayakawa, K., Funatsu, T.
  • Journal Title: Chromatographia (in press)
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Long-Range Transportation of Polycyclic Aromatic Hydrocarbons from China to Japan.
  • Author(s): Yang, X.-Y., Okada, Y., Tang, N., Matsunaga, S., Tamura, K., Kameda, T., Toriba, A., Hayakawa, K.
  • Journal Title: Atmos. Environ. (in press)
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Environmental quinoid polycyclic aromatic hydrocarbon, acenaththenequinone, modulates COX expression through ROS generation and NF-κB activation in A549 cells.
  • Author(s): Chung, S.-W., Chung, H.-Y., Toriba, A., Hayakawa, K.
  • Journal Title: Toxicol. Sci. (in press)
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Study on atmospheric polycyclic aromatic hydrocarbons at a background site of Ishikawa prefecture. Japan.
  • Author(s): Yang, X.-Y., Okada, Y., Tang, N., Toriba, A., Hayakawa K.
  • Journal Title: J. Ecotech. Research (in press)
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] A Determination Method for Nitrocatecholamines in Rat Brain with High-Performance Liquid Chromatography- Peroxyoxalate Chemiluminescence Detection.
  • Author(s): Tsunoda, M., Uchino, E., Imai, K., Hayakawa, K., Funatsu, T.
  • Journal Title: Chromatographia (in press)
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Long-Range Transportation of Polycyclic Aromatic Hydrocarbons from China to Japan.
  • Author(s): Yang, X.-Y, Okada, Y, Tang, N., Matsunaga, S., Tamura, K., Kameda, T., Toriba, A., Hayakawa, K.
  • Journal Title: Atmos. Environ. (in press)
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Environmental quinoid polycyclic aromatic hydrocarbon, acenaththenequinone, modulates COX expression through ROS generation and NF-kB activation in A549 cells.
  • Author(s): Chung, S.-W, Chung, H.-Y, Toriba, A., Hayakawa, K.
  • Journal Title: Toxicol. Sci. (in press)
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Polycyclic Aromatic Hydrocarbons and Their Nitrated Derivatives in Three Typical Cities, Liaoning Province, China.
  • Description: 「研究成果報告書概要(欧文)」より
• [Book] 水環境ハンドブック (2006)
  • Author(s): 川西琢也(分担:水環境学学会編)
  • Total Pages: 736
  • Publisher: 朝倉書店
  • Description: 「研究成果報告書概要(和文)」より
• [Book] Past, Present and Future Environments of Pan-Japan Sea Region. (2006)
  • Author(s): Kawanishi, T.et al., in Hayakawa, K.et al.eds.
  • Total Pages: 605
  • Publisher: Maruzen
  • Description: 「研究成果報告書概要(和文)」より
• [Book] エネルギー・環境キーワード辞典-分野別用語一覧付 (2005)
  • Author(s): 川西琢也(分担:エネルギー学会編)
  • Total Pages: 480
  • Publisher: コロナ社
  • Description: 「研究成果報告書概要(和文)」より