2006 Fiscal Year Final Research Report Summary
Development of adsorption device for highly hydrophilic cyanobacteria toxins and clean-up of aqueous environment
| Project/Area Number |
16350082
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Environmental chemistry
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| Research Institution | Kyoto Institute of Technology |
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Principal Investigator |
HOSOYA Ken Tohoku University, Graduate School of Environmental Studies, Associate Professor, 環境科学研究科, 助教授 (00209248)
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| Project Period (FY) |
2004 – 2006
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| Keywords | Interval Immobilization Technique / Pseudo template molecule / Molecularly imprinted polymer / Cylindrospermopsin / Cyanobacterium toxins / Co-continuous media / Eutrophication / Biodegradable polymer |
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| Research Abstract |
(1) Preparation of selective molecular recognition sites by "Interval Immobilization Technique"
A novel adsorption medium containing selective molecular recognition site for one of the powerful cyanobacterium toxins, Cylindrospermopsin (CYN) was developed using a special technique, namely interval immobilization technique. The adsorption medium was prepared using molecular assembly derived from an alternative-template molecule coupled with functional monomers for fixing the interval between the ionic functional groups in CYN. As results of liquid chromatographic evaluations, selective molecular recognition ability for CYN was observed as expected.
(2) Development of analytical system for concentration of the target molecule followed by chromatographic analysis
Uniformly sized molecularly imprinted polymers (MIPs) with surface modification and immobilized intervals of functional monomers have been prepared. Prepared MIPs showed significant selectivity for the target molecule and removal performance for interference in actual samples as the HPLC stationary phase compared to those of ordinary MIPs. The HPLC system provided a detection limit of 0.36 ppt when electrochemical detection was used.
(3) Preparation of biodegradable adsorption media and its application
We have to develop an adsorbent for the sake of removing nitric acid and phosphoric acid from natural river water to reduce this environmental problem. Although only a small amount of the adsorbent was applied to a river, 81% of nitric acid and 52% of phosphoric acid were removed from the natural river water continuously for 3 months.
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[Journal Article] Simple and comprehensive two-dimensional reversed-phase HPLC using monolithic silica columns.2004
Author(s)
N.Tanaka, H.Kimura, D.Tokuda, K.Hosoya, T.Ikegami, N.Ishizuka, H.Minakuchi, K.Nakanishi, Y.Shintani, M.Furuno, K.Cabrera
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Journal Title
Anal.Chem. 76
Pages: 1273-1281
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Simple 2D-HPLC using a monolithic silica column for peptide separation.2004
Author(s)
H.Kimura, T.Tanigawa, H.Morisaka, T.Ikegami, K.Hosoya, N.Ishizuka, H.Minakuchi, K.Nakanishi, M.Ueda, K.Cabrera, N.Tanaka
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Journal Title
J.Separation Sci. 27
Pages: 894-904
Description
「研究成果報告書概要(欧文)」より
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