Studies on development, structure and function of pituitary gland in amphibians

2005 Fiscal Year Final Research Report Summary

• Project/Area Number: 16370031
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Morphology/Structure
• Research Institution: Waseda University
• Principal Investigator: KIKUYAMA Sakae Waseda University, School of Education, Professor, 教育・総合科学学術院・教育学部, 教授 (20063638)
• Co-Investigator(Kenkyū-buntansha): KATO Takashi Waseda University, School of Education, Professor, 教育・総合科学学術院・教育学部, 教授 (80350388) ; OKADA Reiko Waseda University, School of Education, Research Associate, 教育・総合科学学術院・教育学部, 助手 (50386554) ; IWATA Takeo Waseda University, School of Education, Research Associate, 教育・総合科学学術院・教育学部, 助手 (10350399) ; KOUKI Tomu Waseda University, School of Human Sciences, Research Associate, 人間科学学術院・人間科学部, 助手 (70350436)
• Project Period (FY): 2004 – 2005
• Keywords: Hypophysis / Amphibian / Development / Structure and function / Reproductive behavior / Hypothalamus

Research Abstract

1.Ontogenic study of pituitary gland
As a tool for tracing the cells that migrate with pituitary primordium but remain in the foregut region, transgenic toads (Xenopus laevis) that express GFP were prepared.
2.Central action of prolactin
An adenohypophyseal hormone prolactin is involved in eliciting courtship behavior in the newt, genus Cynops, acting centrally. As a step to elucidate the mechanism of the prolactin action, distribution of prolactin receptors in the newt (Cynops pyrrhogaster) brain was studied by immunohistochemistry and in situ hybridization. Immunohistochemically detectable prolactin receptors as well as prolactin receptor mRNAs were observed in several region of hypothalamic nuclei, and most notably in the choroid plexus. Involvement of choroid plexus in transporting prolactin molecules into the brain was suggested.
3.Regulation of pituitary function by hypothalamic neuropeptides
Newly developed radioimmunoassay for amphibian TSH made it possible to detect TSH-releasing factors in the amphibian brain. As a result, CRF was revealed to be the most potent substance to stimulate the release of TSH from the bullfrog pituitary. Using CRF antagonists and agonists, CRF receptor type 2 was demonstrated to mediate the action of CRF to release TSH.

Research Products

• [Journal Article] Localization of prolactin receptor in the newt brain. (2005)
  • Author(s): Hasunuma, I. et al.
  • Journal Title: Cell Tissue Res. 320 Pages: 477-485
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Expression of aromatase mRNA in the abdominal gland of the newt, Cynops pyrrhogaster. (2005)
  • Author(s): Ito, Y.et al.
  • Journal Title: Ann. N. Y. Acad. Sci. 1040 Pages: 348-350
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Regionally specific occurrence of an active sodefrin variant in the red-belied newt. (2005)
  • Author(s): Iwata, T. et al.
  • Journal Title: Ann. N. Y. Acad. Sci. 1040 Pages: 351-353
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Thyroid hormones inhibit frog corticotropin-releasing factor-induced thyrotropin release from the bullfrog pituitary in vitro. (2005)
  • Author(s): Kaneko, M. et al.
  • Journal Title: Gen. Comp. Endocrinol. 144 Pages: 122-127
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Amphibian pheromones and endocrine control of their secretion. (2005)
  • Author(s): Kikuyama, S. et al.
  • Journal Title: Ann. N. Y. Acad. Sci. 1040 Pages: 123-130
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Monoaminergic neuronal development is not affected in PACAP gene-deficient mice. (2005)
  • Author(s): Ogawa, T. et al.
  • Journal Title: Regul. Pept. 126 Pages: 103-108
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Pituitary adenylate cyclase-activating polypeptide promotes differentiation of mouse neural stem cells into astrocytes. (2005)
  • Author(s): Ohno, F. et al.
  • Journal Title: Regul. Pept. 126 Pages: 115-122
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Frog corticotropin-releasing hormone (CRH) : isolation, molecular cloning, and biological activity. (2005)
  • Author(s): Okada, R. et al.
  • Journal Title: Ann. N. Y. Acad. Sci. 1040 Pages: 150-155
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Expression of erythropoietin receptor-like molecule in Xenopus laevis and erythrocytopenia upon administration of its recombinant soluble form. (2005)
  • Author(s): Aizawa, Y. et al.
  • Journal Title: J. Biochem. 138 Pages: 167-175
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Prolactin acts centrally to enhance newt courtship behavior. (2005)
  • Author(s): Toyoda, F. et al.
  • Journal Title: Gen. Comp. Endocrinol. 141 Pages: 172-177
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Localization of prolactin receptor in the newt brain. (2005)
  • Author(s): Hasunuma, I., Toyoda, F., Yamamoto, K., Yamashita, M., Kikuyama, S.
  • Journal Title: Cell Tissue Res. 320 Pages: 477-485
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Expression of aromatase mRNA in the abdominal gland of the newt, Cynops pyrrhogaster. (2005)
  • Author(s): Ito, Y., Hirota, A., Nakamura, M., Matsunaga, M., Tsutsui, K., Kikuyama, S.
  • Journal Title: Ann.N.Y.Acad.Sci. 1040 Pages: 348-350
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Thyroid hormones inhibit frog corticotropin-releasing factor-induced thyrotropin release from the bullfrog pituitary in vitro. (2005)
  • Author(s): Kaneko, M., Fujisawa, H., Okada, R., Yamamoto, K., Nakamura, M., Kikuyama, S.
  • Journal Title: Ann.N.Y.Acad.Sci. 1040 Pages: 351-353
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Amphibian pheromones and endocrine control of their secretion. (2005)
  • Author(s): Kikuyama, S., Nakada, T., Toyoda, F., Iwata, T., Yamamoto, K., Conlon, J.M.
  • Journal Title: Gen.Comp.Endocrinol. 144 Pages: 122-127
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Monoaminergic neuronal development is not affected in PACAP gene-deficient mice. (2005)
  • Author(s): Ogawa, T., Nakamachi, T., Ohtaki, H., Hashimoto, H., N, S., Baba, A., Watanabe, J., Kikuyama, S., Shioda, S.
  • Journal Title: Ann.N.Y.Acad.Sci. 1040 Pages: 123-130
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Pituitary adenylate cyclase-activating polypeptide promotes differentiation of mouse neural stem cells into astrocytes. (2005)
  • Author(s): Ohno, F., Watanabe, J., Sekihara, H., Hirabayashi, T., Arata, S., Kikuyama, S., Shioda, S., Nakaya, K., Nakajo, S.
  • Journal Title: Regul.Pept. 126 Pages: 103-108
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Frog corticotropin-releasing hormone (CRH) : isolation, molecular cloning, and biological activity. (2005)
  • Author(s): Okada, R., Ito, Y., Kaneko, M., Yamamoto, K., Chartrel, N., Conlon, J.M., Vaudry, H., Kikuyama, S.
  • Journal Title: Ann.N.Y.Acad.Sci. 1040 Pages: 150-155
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Expression of erythropoietin receptor-like molecule in Xenopus laevis and erythrocytopenia upon administration of its recombinant soluble form. (2005)
  • Author(s): Aizawa, Y., Nogawa, N., Kosaka, N., Maeda, Y., Watanabe, T., Miyazaki, H., Kato, T.
  • Journal Title: J.Biochem. 138 Pages: 167-175
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Prolactin acts centrally to enhance newt courtship behavior. (2005)
  • Author(s): Toyoda, F., Hasunuma, I., Yamamoto, K., Yamashita, M., Kikuyama, S.
  • Journal Title: Gen.Comp.Endocrinol. 141 Pages: 172-177
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Hormonal regulation of growth in amphibians. (Biology of Amphibians (2005)
  • Author(s): Kikuyama, S., Yamamoto, K., Kobayashi, T., Tenon, M.-C., Galas, L., Vaudry, H.
  • Journal Title: Endocrinology of Amphibians (H. Heatwale, Ed.)(Surrey Beatty and Sons, Chipping Norton (Australia)) vol.6 Pages: 2267-2300
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Molecular cloning of bullfrog prolactin receptor cDNA : changes in prolactin receptor mRNA level during metamorphosis. (2004)
  • Author(s): Hasunuma, I. et al.
  • Journal Title: Gen. Comp. Endocrinol. 138 Pages: 200-210
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Molecular cloning of bullfrog corticotropin-releasing factor (CRF) : effect of homologous CRF on the release of TSH from pituitary cells in vitro. (2004)
  • Author(s): Ito, Y.et al.
  • Journal Title: Gen. Comp. Endocrinol. 138 Pages: 218-227
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Processing of multiple forms of preprosodefrin in the abdominal gland of the red-bellied newt Cynops pyrrhogaster : regional and individual differences in preprosodefrin. (2004)
  • Author(s): Iwata, T. et al.
  • Journal Title: Peptides 25 Pages: 1537-1543
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Expression of prolactin receptor mRNA in the abdominal gland of the newt Cynops ensicauda. (2004)
  • Author(s): Matsukawa, H. et al.
  • Journal Title: Comp. Biochem. Physiol. A 138 Pages: 79-88
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Effect of pituitary adenylate cyclase-activating polypeptide 38 (PACA38) on tissue oxygen content-Treatment in central nervous system of mice. (2004)
  • Author(s): Ohtaki, H. et al.
  • Journal Title: Regul. Pept. 123 Pages: 61-67
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Development of radioimmunoassay for bullfrog thyroid-stimulating hormone (TSH) : effects of hypothalamic releasing hormones on the release of TSH from the pituitary in vitro. (2004)
  • Author(s): Okuda, R. et al.
  • Journal Title: Gen. Comp. Endocrinol. 135 Pages: 42-50
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Multihormonal control of vitellogenesis in lower veterbrates. (2004)
  • Author(s): Polzonetti, M.A. et al.
  • Journal Title: Int. Rev. Cytol. 239 Pages: 1-46
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Possible direct induction by estrogen of calcitonin secretion from ultimobranchial cells in the goldfish. (2004)
  • Author(s): Suzuki, N. et al.
  • Journal Title: Gen. Comp. Endocrinol. 138 Pages: 121-127
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Effect of bullfrog LH and FSH on newt testes under different temperatures. (2004)
  • Author(s): Tanaka, S. et al.
  • Journal Title: Gen. Comp. Endocrinol. 138 Pages: 1-7
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Peptide pheromones in newts. (2004)
  • Author(s): Toyoda, F. et al.
  • Journal Title: Peptides 25 Pages: 1531-1536
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Localization of orexin-A like immunoreacitivity in prolactin cells in the bullfrog (Rana catesbeiana) pituitary. (2004)
  • Author(s): Yamamoto, K. et al.
  • Journal Title: Gen. Comp. Endocrinol. 135 Pages: 186-192
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Possible existence of processing enzymes generating sodefrin molecule in the abdominal gland. (2004)
  • Author(s): Ishizuka, Y. et al.
  • Journal Title: Trends in Comparative Endocrinology (T. Oishi, K. Tsutsui, S. Tanaka, S. Kikuyama, Eds) Pages: 426-428
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Otoconin and chitinase : digression from amphibian pituitary research. (2004)
  • Author(s): Kikuyama, S. et al.
  • Journal Title: Trends in Comparative Endocrinology (T. Oishi, K. Tsutsui, S. Tanaka, S. Kikuyama, Eds) Pages: 6-9
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Effects of hypothalamic factors of the release of TSH bullfrog pituitary cells (2004)
  • Author(s): Okada, R. et al.
  • Journal Title: Trends in Comparative Endocrinology (T. Oishi, K. Tsutsui, S. Tanaka, S. Kikuyama, Eds) Pages: 245-247
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Molecular cloning of bullfrog corticotropin-releasing hormone cDNA. (2004)
  • Author(s): Ito, Y.et al.
  • Journal Title: Trends in Comparative Endocrinology (T. Oishi, K. Tsutsui, S. Tanaka, S. Kikuyama, Eds) Pages: 248-250
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Localization of prolactin receptor in the newt brain. (2004)
  • Author(s): Hasunuma, I. et al.
  • Journal Title: Trends in Comparative Endocrinology (T. Oishi, K. Tsutsui, S. Tanaka, S. Kikuyama, Eds) Pages: 257-259
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] n vitro effect of bisphenol A on the thyroid hormone receptor gene expression in the Xenopus tail and testis. (2004)
  • Author(s): Iwamuro, S. et al.
  • Journal Title: Trends in Comparative Endocrinology (T. Oishi, K. Tsutsui, S. Tanaka, S. Kikuyama, Eds) Pages: 590-593
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Detection of sodefrin-responsive cell in the newt vomeronasal epithelium by calsium imaging. (2004)
  • Author(s): Iwata, E. et al.
  • Journal Title: Trends in Comparative Endocrinology (T. Oishi, K. Tsutsui, S. Tanaka, S. Kikuyama, Eds) Pages: 432-434
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Prolactin induces courtship behavior in the male newts acting centrally. (2004)
  • Author(s): Toyoda, F. et al.
  • Journal Title: Trends in Comparative Endocrinology (T. Oishi, K. Tsutsui, S. Tanaka, S. Kikuyama, Eds) Pages: 46-48
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Effects of RF-amide peptides on the release of TSH from the bullfrog pituitary. (2004)
  • Author(s): Yamamoto, K. et al.
  • Journal Title: Trends in Comparative Endocrinology (T. Oishi, K. Tsutsui, S. Tanaka, S. Kikuyama, Eds) Pages: 298-300
  • Description: 「研究成果報告書概要(和文)」より
• [Journal Article] Molecular cloning of bullfrog prolactin receptor cDNA : changes in prolactin receptor mRNA level during metamorphosis. (2004)
  • Author(s): Hasunuma, I., Yamamoto, K., Kikuyama, S.
  • Journal Title: Gen.Comp.Endocrinol. 138 Pages: 200-210
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Molecular cloning of bullfrog corticotropin-releasing factor (CRF) : effect of homologous CRF on the release of TSH from pituitary cells in vitro. (2004)
  • Author(s): Ito, Y., Okada, R., Mochida, H., Hayashi, H., Yamamoto, K., Kikuyama, S.
  • Journal Title: Gen.Comp.Endocrinol. 138 Pages: 218-227
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Processing of multiple forms of preprosodefrin in the abdominal gland of the red-bellied newt Cynops pyrrhogaster : regional, individual differences in preprosodefrin. (2004)
  • Author(s): Iwata, T., Conlon, J.M., Nakada, T., Toyoda, F., Yamamoto, K., Kikuyama, S.
  • Journal Title: Peptides 25 Pages: 1537-1543
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Expression of prolactin receptor mRNA in the abdominal gland of the newt Cynops ensicauda. (2004)
  • Author(s): Matsukawa, H., Hasunuma, I., Kato, T., Yamamoto, K., Miura, S., Fujita, T., Kikuyama, S.
  • Journal Title: Comp.Biochem.Physiol.A 138 Pages: 79-88
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Effect of pituitary adenylate cyclase-activating polypeptide 38 (PACAP38) on tissue oxygen content--Treatment in central nervous system of mice. (2004)
  • Author(s): Ohtaki, H., Dohi, K., Yofu, S., Nakamachi, T., Kudo, Y., Endo, S., Aruga, T., Goto, N., Watanabe, J., Kikuyama, S., Shioda, S.
  • Journal Title: Regul.Pept. 123 Pages: 61-67
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Development of radioimmunoassay for bullfrog thyroid-stimulating hormone (TSH) : effects of hypothalamic releasing hormones on the release of TSH from the pituitary in vitro. (2004)
  • Author(s): Okada, R., Yamamoto, K., Koda, A., Ito, Y., Hayashi, H., Tanaka., S., Hanaoka, Y., Kikuyama, S.
  • Journal Title: Gen.Comp.Endocrinol. 135 Pages: 42-50
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Multihormonal control of vitellogenesis in lower vertebrates. (2004)
  • Author(s): Polzonetti, M.A., Mosconi, G., Soverchia, L., Kikuyama, S., Comevalli, O.
  • Journal Title: Int.Rev.Cytol. 239 Pages: 1-46
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Possible direct induction by estrogen of calcitonin secretion from ultimobranchial cells in the goldfish. (2004)
  • Author(s): Suzuki, N., Yamamoto, K., Sasayama, Y., Suzuki, T., Kurokawa, T., Kambegawa, A., Srivastav, A.K., Hayashi, S., Kikuyama, S.
  • Journal Title: Gen.Comp.Endocrinol. 138 Pages: 121-127
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Effect of bullfrog LH and FSH on newt testes under different temperatures. (2004)
  • Author(s): Tanaka, S., Sakai, M., Hattori, M., Kikuyama, S., Wakabayashi, K., Hanaoka, Y.
  • Journal Title: Gen.Comp.Endocrinol. 138 Pages: 1-7
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Peptide pheromones in newts. (2004)
  • Author(s): Toyoda, F., Yamamoto, K., Iwata, T., Hasunuma, I., Cardinali, M., Mosconi, G., Polzonetti-Magni, A.M., Kikuyama, S.
  • Journal Title: Peptides 25 Pages: 1531-1536
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Localization of orexin-A like immunoreactivity in prolactin cells in the bullfrog (Rana catesbeiana) pituitary. (2004)
  • Author(s): Yamamoto, T., Suzuki, H., Uemura, H., Yamamoto, K., Kikuyama, S.
  • Journal Title: Gen.Comp.Endocrinol. 135 Pages: 186-192
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Possible existence of processing enzymes generating sodefrin molecule in the abdominal gland. (2004)
  • Author(s): Ishizuka, Y., Iwata, T., Conlon, J.M., Toyoda, F., Nakada, T., Yamamoto, K., Kikuyama, S.
  • Journal Title: Trends in Comparative Endocrinology (T.Oishi, K.Tsutsui, S.Tanaka, S.Kikuyama, Eds), Asia Oceania Society for Comparative Endocrinology. Pages: 426-428
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Otoconin and chitinase : digression from amphibian pituitary research. (2004)
  • Author(s): Kikuyama, S., Yaoi, Y., Tanaka, S., Sakai, M., Hayashi, H., Oshima, H., Kawamura, K.
  • Journal Title: Trends in Comparative Endocrinology (T.Oishi, K.Tsutsui, S.Tanaka, S.Kikuyama, Eds), Asia Oceania Society for Comparative Endocrinology. Pages: 6-9
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Effects of hypothalamic factors of the release of TSH from bullfrog pituitary cells. (2004)
  • Author(s): Okada, R., Ito, Y., Fujisawa, H., Tanaka, S., Yamamoto, K., Kikuyama, S.
  • Journal Title: Trends in Comparative Endocrinology (T.Oishi, K.Tsutsui, S.Tanaka, S.Kikuyama, Eds), Asia Oceania Society for Comparative Endocrinology. Pages: 245-247
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Molecular cloning of bullfrog corticotropin-releasing hormone cDNA. (2004)
  • Author(s): Ito, Y., Okada, R., Yamamoto, K., Kikuyama, S.
  • Journal Title: Trends in Comparative Endocrinology (T.Oishi, K.Tsutsui, S.Tanaka, S.Kikuyama, Eds), Asia Oceania Society for Comparative Endocrinology. Pages: 248-250
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Localization of prolactin receptor in the newt brain. (2004)
  • Author(s): Hasunuma, I., Toyoda, F., Yamamoto, K., Kikuyama, S.
  • Journal Title: Trends in Comparative Endocrinology (T.Oishi, K.Tsutsui, S.Tanaka, S.Kikuyama, Eds), Asia Oceania Society for Comparative Endocrinology. Pages: 257-259
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] In vitro effect of bisphenol A on the thyroid hormone receptor gene expression in the Xenopus tail and testis. (2004)
  • Author(s): Iwamuro, S., Aikawa, N., Yamada, M., Kikuyama, S.
  • Journal Title: Trends in Comparative Endocrinology (T.Oishi, K.Tsutsui, S.Tanaka, S.Kikuyama, Eds), Asia Oceania Society for Comparative Endocrinology. Pages: 590-593
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Detection of sodefrin-responsive cell in the, newt vomeronasal epithelium by calcium imaging. (2004)
  • Author(s): Iwata, T., Yada, T., Shioda, S., Toyoda, F., Kikuyama, S.
  • Journal Title: Trends in Comparative Endocrinology (T.Oishi, K.Tsutsui, S.Tanaka, S.Kikuyama, Eds), Asia Oceania Society for Comparative Endocrinology. Pages: 432-434
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Prolactin induces courtship behavior in the male newts acting centrally. (2004)
  • Author(s): Toyoda, F., Hasunuma, H., Yamamoto, K., Yamashita, M., Kikuyama, S.
  • Journal Title: Trends in Comparative Endocrinology (T.Oishi, K.Tsutsui, S.Tanaka, S.Kikuyama, Eds), Asia Oceania Society for Comparative Endocrinology. Pages: 46-48
  • Description: 「研究成果報告書概要(欧文)」より
• [Journal Article] Effects of RF-amide peptides on the release of TSH from the bullfrog pituitary. (2004)
  • Author(s): Yamamoto, K., Koda, A., Ukena, K., Okada, R., Iwakoshi-Ukena, E., Minakata, H., Tsutsui, K., Kikuyama, S.
  • Journal Title: Trends in Comparative Endocrinology (T.Oishi, K.Tsutsui, S.Tanaka, S.Kikuyama, Eds), Asia Oceania Society for Comparative Endocrinology. Pages: 298-300
  • Description: 「研究成果報告書概要(欧文)」より
• [Book] Hormonal regulation of growth in amphibians. In "Biology of Amphibians vol. 6 : Endocrinology of Amphibians" (H. Heatwale, Ed.) (2005)
  • Author(s): Kikuyama, S. et al.
  • Publisher: Surrey Beatty and Sons, Chipping Norton (Australia)
  • Description: 「研究成果報告書概要(和文)」より