2007 Fiscal Year Final Research Report Summary
Oral health and subsequent risk of lifestyle-related diseases : a cohort study in Japanese dentists
| Project/Area Number |
16390189
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Public health/Health science
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| Research Institution | Nagoya University (2006-2007)
Aichi Cancer Center Research Institute (2004-2005) |
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Principal Investigator |
WAKAI Kenji Nagoya University, Graduate School of Medicine, Associate Professor (50270989)
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| Co-Investigator(Kenkyū-buntansha) |
KAWAMURA Takashi Kyoto University, Health Service, Professor (10252230)
NAITO Mariko Nagoya University, Graduate School of Medicine, Associate Professor (10378010)
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| Project Period (FY) |
2004 – 2007
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| Keywords | oral health / dentist / cohort study / tooth loss / nutrient intake / mortality / stroke / ischemic heart disease |
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| Research Abstract |
To elucidate the relevance of oral health with subsequent risk of lifestyle-related diseases, we are conducting a cohort study in Japanese dentists. The information on oral status could be collected with a self-administered questionnaire from the participants, and they have been followed-up through their affiliated dental associations. In this project, we examined the correlates of tooth loss and the association between tooth loss and nutrient intake in a cross-sectional study utilizing the baseline data In addition, the associations of tooth loss with the total mortality and the incidence of stroke and ischemic heart diseases were assessed by analyzing the cohort data. A total of 21,272 dentists (mean age ± SD, 522 ± 12.3 years ; women, 8.0%) participated in this study Age, female sex, smoking, history of diabetes, and systolic blood pressure were positively correlated with the risk of tooth loss (≧5 teeth) while use of floss, frequency of sealing, and vigorous exercise were inversely linked to the risk The adjusted geometric means in nutrient intakes were higher among those with more present teeth except for carbohydrate. The significantly increased risk of total death (age and sex-adjusted mortality rate ratio, 1.3-1.6) was found in relation to the loss of more than five teeth compared with that of less than five. Although the adjustment for confounding factors attenuated this association, the higher mortality rate ratio was still observed in those with more tooth loss. The age and sex-adjusted risk of incident stroke was also correlated with the number of lost teeth, but the correlation was attenuated after adjustment for other confounders. Although a further follow-up is warranted, this study suggests the bilateral association between oral health and general wellbeing.
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Research Products
(18 results)
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[Journal Article] A cohort study on oral health, general wellbeing, and nutrition among dentists : aiming to provide evidence from dental practicians2005
Author(s)
Wakai, K, Kawamura, T, Naito, M, Naito, T, Kojirna, M, Nakagaki, H, Umemura, O, Yokota, M, Hanada, N
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Journal Title
Journal of Japan Dental Association 58
Pages: 865-873
Description
「研究成果報告書概要(欧文)」より
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[Presentation] A cohort study on associations among oral health, general wellbeing, and nutrition in dentists (LEMONADE Study) : study design and characteristics of participants2008
Author(s)
Wakai, K, Naito, M, Naito, T, Nakagaki, H, Umemura, O, Yokota, M, Hanada, N, Kawamura, T
Organizer
The 18th Scientific Meeting of the Japan Epidemiological Association
Place of Presentation
Tokyo
Year and Date
2008-01-26
Description
「研究成果報告書概要(欧文)」より
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[Presentation] The associations of oral health-related quality of life with psychological distress and general health among Japanese2007
Author(s)
Naito, M, Wakai, K, Kawamura, T, Naito, T, Suzukamo, Y, Nakayama, T, Fukuhara, S
Organizer
The 14th Annual Meeting of the International Society for Quality of Life Research
Place of Presentation
Toronto
Year and Date
20071010-13
Description
「研究成果報告書概要(欧文)」より
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[Presentation] Associations of obesity with periodontal disease in the baseline survey of the dentist cohort study2007
Author(s)
Naito, T, Wakai, K, Naito, M, Kawamura, T, Yoneda, M, Suzuki, N, Yokota, M, Hirofuji, T
Organizer
The 50th Anniversary Meeting of the Japanese Society of Periodontology
Place of Presentation
Tokyo
Year and Date
20070921-22
Description
「研究成果報告書概要(欧文)」より
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[Presentation] The influence of tooth loss on the nutrition and total mortality of dentists2007
Author(s)
Wakai, K, Naito, M, Naito, T, Kojima, M, Nakagaki, H, Umemura, O, Yokota, M, Hanada, N, Kawamura, T
Organizer
The 39 th Conference of Asia-Pacific Academic Consortium for Public Health
Place of Presentation
Sakado
Year and Date
2007-09-23
Description
「研究成果報告書概要(欧文)」より
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[Presentation] The dentist cohort study : a longitudinal study on oral health and general wellbeing, mental stress, and nutrition2004
Author(s)
Naito, T, Sato, N, Wakai, K, Kawamura, T, Naito, M, Nagata, M, Akiyama, H, Hanada, N, Umemura, O, Yokota, M
Organizer
The 20th General Meeting of the Japanese Association for Dental Science
Place of Presentation
Yokohama
Year and Date
20041029-31
Description
「研究成果報告書概要(欧文)」より
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