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2006 Fiscal Year Final Research Report Summary

Optimal exercise intensity for defense ability to oxidative stress

Research Project

Project/Area Number 16500397
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Sports science
Research InstitutionThe University of Electro-Communications

Principal Investigator

NAGASAWA Junichi  The University of Electro-Communications, Faculty of Electro-Communications, Associate Professor, 電気通信学部, 助教授 (40228002)

Co-Investigator(Kenkyū-buntansha) IZAWA Tetsuya  Tokyo Metroporitan University, Faculty of Health Promotion Science, Professor, 大学院理学研究科, 教授 (70147495)
OHNO Hideki  Korin University, Department of Medicine, Professor, 医学部, 教授 (00133819)
Project Period (FY) 2004 – 2006
Keywordsactive oxygen / physical exercise / lactate
Research Abstract

The purpose of the study was to evaluate the effects of physical exercise to antioxidation power in plasma. Six male subjects (21-25 years old) performed maximal exercise by a gradual increase load using a bicycle ergometer. Exercise load was raised by 25W every four minutes to exhaustion. Blood samples were obtained from the antecubital vein at rest, each load stage, and 10 minutes, 1-hour and 1-day after exercise. As antioxidation power, we measured iron reduction power (Fe^<3+>→Fe^<2+>). The quantity of hydroxyl radical generation was measured by a spin trap method. The lactic acid and the pyruvic acid were measured by an enzyme method. Six another subjects exercised with a physical work as equivalence. The iron reduction power in plasma rose with an increase in exercise intensity. On the contrary, the quantity of generation of a hydroxyl radical decreased with a rise of exercise intensity. This shows that antioxidation power of plasma increases by a rise of exercise intensity. In addition, there were negative relations to lactic acid and ESR signal intensity. These data supported that the plasma lactic acid which increased by exercise has a role of a scavenger of active oxygen.

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Published: 2008-05-27  

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