Relationship between daily physical-activity, and visceral fat accumulation in consideration of genetic factors

2005 Fiscal Year Final Research Report Summary

• Project/Area Number: 16500453
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Applied health science
• Research Institution: Prefectural University of Hiroshima (2005); Hiroshima Prefectual College of Health Sciences (2004)
• Principal Investigator: DOMOTO Tokio Prefectural University of Hiroshima, Faculty of Health and Welfare, Professor, 保健福祉学部, 教授 (40112130)
• Co-Investigator(Kenkyū-buntansha): KOYAMA Tadasi Prefectural University of Hiroshima, Faculty of Health and Welfare, Professor, 保健福祉学部, 教授 (30034044) ; KATOU Youji Prefectural University of Hiroshima, Faculty of Health and Welfare, Assistant Professor, 保健福祉学部, 助手 (60326436) ; YASUTAKE Sigeru Prefectural University of Hiroshima, Faculty of Health and Welfare, Professor, 保健福祉学部, 教授 (70382380) ; KASAGI Keiko Prefectural University of Hiroshima, Faculty of Health and Welfare, Associate Professor, 保健福祉学部, 助教授 (30101471) ; NISIHARA Sadamitsu Prefectural University of Hiroshima, Faculty of Health and Welfare, Assistant Professor, 保健福祉学部, 助手 (40290548)
• Project Period (FY): 2004 – 2005
• Keywords: daily physical-activity / physical measurements / leptin / β 3 adrenergic receptor gene / % fat / visceral fat / MRI / Lifedorder

Research Abstract

The purpose of this study was to estimate several indications concerning the obesity correlated with visceral fat accumulation. And correlationship between daily physical-activity and visceral fat accumulation were examined in-relation with 13-adrenergic receptor genotypes. The subjects were 73 community-dwelling females (mean age±SD, 51±6 ). They worn the pedometer (Lifecorder) on the waist and performed daily life for about 2 months, before measuring BMI, % fat, abdominal subcutaneous and visceral fat by MRI, waist circumstance length, plasma leptin concentration. Highly correlation coefficients were shown between visceral fat area (by MRI) and BMI, % fat, waist circumstance length and plasma leptin concentration. According the average daily steps, 4 groups were classified into (1)less than 7000steps, (2)7000-10000steps, (3)10000-13000steps, and (4)more than 13000steps. BMI, % fat, abdominal subcutaneous and visceral fat by MRI, waist circumstance length, plasma leptin concentration were extremely low in the group of more than 13000steps.β-adrenergic receptor genotypes were classified by 64Trp or 64Arg into 3types (TT, TA and AA). TT types were shown in 60 persons, and TA in 6 persons, and AA in only 1 person. There was no direct correlationship between genotype and obesity indications.