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2006 Fiscal Year Final Research Report Summary

Driving evaluation for older adult drivers using NIRS and driving simulator

Research Project

Project/Area Number 16591163
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Psychiatric science
Research InstitutionShowa University

Principal Investigator

MIMURA Masaru  Showa Univ., Neuropsychiatry, Associate Professor, 医学部, 助教授 (00190728)

Co-Investigator(Kenkyū-buntansha) KAWAMURA Mitsuru  Showa Univ., Neurology, Professor, 医学部, 教授 (20161375)
NAKAGOME Kazuyuki  Tottori Univ., Neuropsychiatry, Professor, 精神医学教室, 教授 (30198056)
OTSUBO Tempei  Showa Univ., Neuropsychiatry, Associate Professor, 医学部, 助教授 (20245856)
Project Period (FY) 2004 – 2006
Keywordsdriving / Alzheimer's disease / mild cognitive impairment / NIRS / simulator / aging / frontal lobe / risk
Research Abstract

Background
Police Department of Japan has reported that one third of older adults hold a driver's license. It is essential to appropriately evaluate capability of driving of older adults because of their own safety as well as safety of the public. The present study aimed to evaluate activities of medial and lateral prefrontal cortex of healthy older adults and people with dementia while conducting driving simulation.
Participants and Methods
Participants consisted of 30 healthy older adults who hold driver's license and 8 individuals with dementia. First, oxy-Hb values were monitored by using near-infrared spectroscopy (NIRS)(52 channels, Hitachi ETG4000) while performing on a driving simulator, TEDDY (TOYOTA Central R&D Labs.) as compared to resting state, i.e. passive viewing. Second, oxy-Hb values between non-eventful and high risk driving situations were also compared.
Results
Participants as a group displayed a mild elevation of oxy-Hb on lateral prefrontal cortex while driving as compared to passive viewing. There was no change or even deactivation observed in the medial prefrontal cortex while driving. Moreover, healthy older adults showed a consistent increase in oxy-Hb under the high risk situations where one needed to make brake responses against rushing pedestrians or bikes. They exhibited elevated oxy-Hb values on broader areas of bilateral medial and lateral prefrontal cortex in the high risk situations. Reaction time of people with dementia was significantly delayed as compared to healthy individuals although their patterns of oxy-Hb changes were variable.
Conclusions
Multi-channel NIRS is useful to easily assess and monitor one's activities of prefrontal cortex while conducting driving simulation.

  • Research Products

    (9 results)

All 2006

All Journal Article (8 results) Book (1 results)

  • [Journal Article] Family history of alcoholism and cognitive recovery in subacute withdrawal2006

    • Author(s)
      Moriyama Y, Mimura M, et al.
    • Journal Title

      Psychiatry Clin Neurosci 60・1

      Pages: 85-89

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] Primary alcoholic dementia and alcohol-related dementia2006

    • Author(s)
      Moriyama Y, Mimura M, et al.
    • Journal Title

      Psychogeriatrics 6・3

      Pages: 114-118

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] 初期アルッハイマー病の認知機能障害2006

    • Author(s)
      古田伸夫, 三村 將
    • Journal Title

      老年精神医学雑誌 17・4

      Pages: 385-392

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] うつ病と認知症2006

    • Author(s)
      鳥居成夫, 三村 將
    • Journal Title

      からだの科学 251

      Pages: 45-49

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] 遂行機能とは2006

    • Author(s)
      三村 將
    • Journal Title

      臨床精神医学 35・11

      Pages: 1511-1516

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] 高次脳機能障害2006

    • Author(s)
      三村 將
    • Journal Title

      臨床精神医学 35・12

      Pages: 1726

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] Family history of alcoholism and cognitive recovery in subacute withdrawal2006

    • Author(s)
      Moriyama Y, Mimura M, et al.
    • Journal Title

      Psychiatry Clin Neurosci 60

      Pages: 85-89

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Primary alcoholic dementia and alcohol-related dementia2006

    • Author(s)
      Moriyama Y, Mimura M, et al.
    • Journal Title

      Psychogeriatrics 6

      Pages: 114-118

    • Description
      「研究成果報告書概要(欧文)」より
  • [Book] Memory and Society : Psychological Perspective2006

    • Author(s)
      Mimura M(分担執筆)
    • Total Pages
      229-250
    • Publisher
      Psychology Press, New York
    • Description
      「研究成果報告書概要(和文)」より

URL: 

Published: 2008-05-27  

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