2005 Fiscal Year Final Research Report Summary
Relation between restless-leg symptoms and sleep problems among general population of Japan
| Project/Area Number |
16614018
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
睡眠学
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| Research Institution | National Center of Neurology and Psychiatry |
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Principal Investigator |
UCHIYAMA Makoto National Center of Neurology and Psychiatry, Department of Psychophysiology, Director and Chairman, 精神保健研究所 精神生理部, 部長 (20221111)
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| Co-Investigator(Kenkyū-buntansha) |
TAGAYA Hirokuni National Center of Neurology and Psychiatry, Department of Psychophysiology. Psychofunction Research Section, Group Leader, 精神保健研究所 精神生理部, 室長 (50342928)
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| Project Period (FY) |
2004 – 2005
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| Keywords | sleep / procedural memory / EEG / REM sleep / non-REM sleep / learning / skill acquisition / EEG spectral analysis |
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| Research Abstract |
In the last decade, many studies have reported overnight improvements of various procedural memory functions exclusively after sleep, suggesting that brain activities during sleep have an important role in memory consolidation. Especially, visual discrimination task (VDT) have been studied intensively to clarify the human memory consolidation during sleep. However, there seems to be no agreement about the role of REM and NREM sleeps in the overnight improvement of VDT. In this study, we investigated the relationship between sleep variables and overnight improvement of VDT task under a naturalistic sleep condition. Furthermore, using fast Fourier transform (FFT) of sleep EEG, we investigated detailed features of EEG spectral powers during the sleep after training. We found that alpha band power in the REM sleep was positively related with the overnight improvement, and that the amount of SWS and delta band power in second half of the night were concerned with the overnight improvement. These results suggest that both activated cortical state during REM sleep and inhibited state during NREM sleep contribute overnight consolidation of procedural memory.
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[Journal Article] Epidemiological study of the relationship between sleep disturbances and somatic and psychological complaints among the Japanese general population2006
Author(s)
Asai T, Kaneita Y, Uchiyama M, Takemura S, Asai S, Yokoyama E, Miyake T, Harano S, Suzuki K, Ibuka E, Kaneko A, Tsutsui T, Ohida T
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Journal Title
Sleep and Biological Rhythms 4
Pages: 55-62
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Excessive daytime sleepiness among Japanese General population2005
Author(s)
Kaneita Y, Ohida T, Uchiyama M, Takemura S, Kawahara K, Yokoyama E, Miyake T, Harano S, Suzuki K, Yagi Y, Kaneko A, Tsutsui T, Akashiba T
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Journal Title
J Epidemiol 15
Pages: 1-8
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Diurnal fluctuation of time perseption under 30-h sustained wakefulness2005
Author(s)
Kuriyama K, Uchiyama M, Suzuki H, Tagaya H, Ozaki A, Aritake S, Shibui K, Tan X, Li L, Kamei Y, Takahashi K
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Journal Title
Neuroscience Research vol.53
Pages: 123-128
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Cerebral White Matter Blood Flow Is Constant During Human Non-Rapid Eye Movement Sleep : A Positron Emission Tomographic Study2005
Author(s)
Hiroki M, Uema T, Kajimura N, Ogawa K, Nishikawa M, Kato M, Watanabe T, Nakajima T, Takano H, Imabayashi E, Ohnishi T, Takayama Y, Matsda H, Uchiyama M, Okawa M, Takahashi K, Fukuyama H
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Journal Title
J Appl Physiol 98
Pages: 1846-1854
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] A Missense Variation in Human Casein Kinase I Epsilon Gene that Induces Functional Alteration and Shows an Inverse Association with Circadian Rhythm Sleep Disorders2004
Author(s)
Takano A, Uchiyama M, Kajimura N, Mishima K, Inoue Y, Kamei Y, Kitajima T, Shibui K, Katoh M, Watanabe T, Hashimotodani Y, Nakajima T, Ozeki Y, Hori T, Yamada N, Toyoshima R, Ozaki N, Okawa M, Nagai K, Takahashi K, Isojima Y, Yamauchi T, Ebisawa T
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Journal Title
Neuropsychopharmacology 29
Pages: 1901-1909
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Sleep habits and factors associated with short sleep duration among Japanese high-school students : A community study.2004
Author(s)
Tagaya H, Uchiyama M, Ohida T, Kamei Y, Shibui K, Ozaki A, Tan X, Suzuki H, Aritake S, Li L, Takahashi K
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Journal Title
Sleep and Biological Rhythms 2
Pages: 57-64
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Deactivation by benzodiazepine of the basal forebrain and amygdala in normal humans during sleep : a placebo-controlled [15O]H2O PET study.2004
Author(s)
Kajimura N, Nishikawa M, Uchiyama M, Kato M, Watanabe T, Nakajima T, Hori T, Nakabayashi T, Sekimoto M, Ogawa K, Takano H, Imabayashi E, Hiroki M, Onishi T, Uema T, Takayama Y, Matsuda H, Okawa M, Takahashi K.
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Journal Title
Am J Psychiatry. 161
Pages: 748-751
Description
「研究成果報告書概要(欧文)」より
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[Journal Article] Time estimation during nocturnal sleep in human subjects
Author(s)
Aritake S, Uchiyama M, Tagaya H, Suzuki H, Kuriyama K, Ozaki A, Tan X, Shibui K, Kamei Y, Okubo Y, Takahashi K
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Journal Title
Neuroscience Research 49
Pages: 387-393
Description
「研究成果報告書概要(欧文)」より
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