2017 Fiscal Year Final Research Report
Investigation of human iPS cell derived 3D bone like tissue using hypoxic culture
Project/Area Number |
16H06643
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Research Category |
Grant-in-Aid for Research Activity Start-up
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Allocation Type | Single-year Grants |
Research Field |
Prosthodontics/ Dental materials science and
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Research Institution | Tohoku University |
Principal Investigator |
Okawa Hiroko 東北大学, 大学院歯学研究科, 非常勤講師 (00781296)
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Research Collaborator |
EGUSA Hiroshi 東北大学, 大学院歯学研究科, 教授 (30379078)
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Project Period (FY) |
2016-08-26 – 2018-03-31
|
Keywords | 再生歯学 / iPS細胞 |
Outline of Final Research Achievements |
Induced pluripotent stem cells (iPS cells) are expected as a stem cell source to be used for regenerative medicine of severe alveolar bone loss. In order to develop iPS cells into clinical application, it is necessary to investigate method of osteogenic differentiation of human iPS cells. In this study, we found that hypoxic culture promotes osteogenic differentiation of iPS cells. It is expected that the results of this research will develop into the establishment of new bone augmentation using iPS cells.
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Free Research Field |
歯科補綴学
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