2017 Fiscal Year Final Research Report
Amniotic fluid and serum biomarkers from women with neural tube defect-affected pregnancies
| Project/Area Number |
16H06664
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Neurosurgery
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| Research Institution | University of Tsukuba |
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Principal Investigator |
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| Project Period (FY) |
2016-08-26 – 2018-03-31
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| Keywords | 羊水幹細胞 / 培地 / 培養条件 / 倫理委員会 / 協力病院 |
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| Outline of Final Research Achievements |
We aimed to establish the useful biomarkers to detect early in the utero during pregnancy of human neural tube defect. There are many things to be prepared to start clinical studies. Due to the restriction of the special medium in Japan, we have to change the protocol about the medium to grow amniotic fluid stem cells. Amniomax II is useful medium using amniotic fluid stem cells in the world, also in Japan. Our study is on going to establish the novel in the utero therapy using small molecules to decrease the risks of neural tube defect by epigenetic mechanisms.
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| Free Research Field |
小児神経外科
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