Investigation of novel bio-marker by urine proteomics and establishment for early diagnosis by two-dimensional approach for urological cancer

2017 Fiscal Year Final Research Report

• Project/Area Number: 16H06814
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: Epidemiology and preventive medicine
• Research Institution: Niigata University
• Principal Investigator: Saito Suguru 新潟大学, 医歯学総合研究科, 客員研究員 (50776721)
• Research Collaborator: Yamamoto Tadashi 新潟大学・生体液バイオマーカーセンター, 地域創成推進機構, 特任教授 ; Hirao Yoshitoshi 新潟大学・生体液バイオマーカーセンター, 地域創成推進機構, 特任准教授
• Project Period (FY): 2016-08-26 – 2018-03-31
• Keywords: 尿プロテオミクス / 泌尿器癌 / バイオマーカー

Outline of Final Research Achievements

Throughout this project, we completed that establishment of the technology in novel bio marker investigation and detection for early diagnosis of urological cancer. In the investigation of bio-marker, we established original analysis platform based on urine proteomics, so that we were success to identify the candidate of novel bio-marker with high accuracy. In the detection of bio-marker, we adopted SPR technique for direct detection of bio-marker in the urine sample. These results are important basic skill for early diagnosis of urological cancer. Based on the skills, further development will be estimated for clinical use.

Free Research Field

予防医学