Elucidation of the mechanism of salivary secretion and swallowing promoted by brain gut model and epilepsy treatment

2017 Fiscal Year Final Research Report

• Project/Area Number: 16H07092
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: Orthodontics/Pediatric dentistry
• Research Institution: Kagoshima University
• Principal Investigator: SUGA Mayu 鹿児島大学, 医歯学域附属病院, 助教 (50779973)
• Project Period (FY): 2016-08-26 – 2018-03-31
• Keywords: 唾液分泌 / 嚥下 / 顎口腔機能

Outline of Final Research Achievements

In a previous human study, swallowing events were observed more frequently after intra-esophageal acid infusion than after saline infusion. however, the association between salivation and swallowing events remains poorly investigated to date.We simultaneously recorded salivation and swallowing using an electrode attached to the mylohyoid muscle during vagal afferent stimulation in a physiological range of frequencies. As a result, Vagal afferent stimulation significantly increased salivation and swallowing-like events in a frequency-dependent manner. These results indicate that visceral sensation induces salivation and swallowing-like events through vagal afferent activation.

Free Research Field

歯科矯正学