Relationship Between Anxiety and Fear, And Pathophysiological Voice Analysis for Neuropathy

2019 Fiscal Year Annual Research Report

• Project/Area Number: 16K00369
• Research Institution: The University of Tokyo
• Principal Investigator: 光吉 俊二 東京大学, 大学院工学系研究科(工学部), 特任准教授 (30570262)
• Co-Investigator(Kenkyū-buntansha): 篠原 修二 東京大学, 大学院工学系研究科(工学部), 特任助教 (10325897) ; 中村 光晃 東京大学, 医学部附属病院, 特任助教 (30772975) ; 徳野 慎一 東京大学, 大学院工学系研究科, 特任教授 (40508339)
• Project Period (FY): 2016-04-01 – 2020-03-31
• Keywords: 感情音声 / TOE

Outline of Annual Research Achievements

本年度は、昨年度までの研究成果の社会実装の準備に入った。実際の社会での普及では、アプリケーションを作る企業、その技術を採用する企業の技術者への理解が何より優先される。そのため、実用を想定する医療分野において、各種病態、病理に即した恐怖や感情、ストレスの規格化、数理化の原理を工学技術者が理解できるモデルにする必要があった。特に、アルツハイマーやうつ病では、喜びと恐怖の相転移をテーマに、その様相を数理モデルにした。この数理モデルを論文（Some hypothesis to derive an anti-Einstein field. デジタルハリウッド大学紀要, 第6号, 3-23, 2019）にして発表した。また、アプリケーションや音声解析に必要になるハースト指数とゼロ交差率に基つ音声指標による解析モデルや学習ベクトル量子化を用いた少数データからの識別、新規ニューラルネットワークの開発も行い、論文（A Multi-armed Bandit Algorithm Available in Stationary or Non-stationary Environments Using Self-organizing Maps）（An Agent-based Approach for Cleanup Problem: Analysis of Human-like Behavior）にした。

Research Products

• [Journal Article] Extended Bayesian inference incorporating symmetry bias (2020)
  • Author(s): Shuji Shinohara, Nobuhito Manome, Kouta Suzuki, Ung-il Chung, Tatsuji Takahashi, Pegio-Yukio Gunji, Yoshihiro Nakajima, Shunji Mitsuyoshi
  • Journal Title: Biosystems Volume: Volume 190 Pages: 104-104
  • DOI: 10.1016/j.biosystems.2020.104104
  • Peer Reviewed / Open Access
• [Journal Article] Some hypothesis to derive an anti-Einstein field (2019)
  • Author(s): Shunji Mitsuyoshi, Kosuke Tomonaga, Masatsugu Hashimoto, Yuichi Tei, Tadao Nakamura
  • Journal Title: DHU Journal Volume: Vol.6 Pages: 3-23
  • Peer Reviewed / Open Access
• [Journal Article] A Multi-armed Bandit Algorithm Available in Stationary or Non-stationary Environments Using Self-organizing Maps (2019)
  • Author(s): Nobuhito Manome, Shuji Shinohara, Kouta Suzuki, Kosuke Tomonaga, Shunji Mitsuyoshi
  • Journal Title: Lecture Notes in Computer Science Volume: Vol. 11727 Pages: 529-540
  • DOI: 10.1007/978-3-030-30487-4_41
  • Peer Reviewed / Open Access
• [Journal Article] An Agent-based Approach for Cleanup Problem: Analysis of Human-like Behavior (2019)
  • Author(s): Nobuhito Manome, Shuji Shinohara, Kouta Suzuki, Shunji Mitsuyoshi
  • Journal Title: Communications in Computer and Information Science Volume: Vol. 1088 Pages: 441-448
  • DOI: 10.1007/978-3-030-30712-7_54
  • Peer Reviewed / Open Access
• [Journal Article] Discrimination of bipolar disorders using voice (2019)
  • Author(s): Higuchi M, Nakamura M, Shinohara S, Omiya Y, Takano T, Toda H, Saito T, Yoshino A, Mitsuyoshi S, Tokuno S
  • Journal Title: Pervasive Computing Paradigms for Mental Health. MindCare 2019. Lecture Notes of the Institute for Computer Sciences, Social Informatics and Telecommunications Engineering Volume: 288 Pages: 199-207
  • DOI: 10.1007/978-3-030-25872-6_16
  • Peer Reviewed / Open Access
• [Journal Article] An attempt to estimate depressive status from voice (2019)
  • Author(s): Omiya Y, Takano T, Uraguchi T, Nakamura M, Higuchi M, Shinohara S, Mitsuyoshi S, So M, Tokuno
  • Journal Title: Pervasive Computing Paradigms for Mental Health. MindCare 2019. Lecture Notes of the Institute for Computer Sciences, Social Informatics and Telecommunications Engineering Volume: 288 Pages: 168-175
  • DOI: 10.1007/978-3-030-25872-6_13
  • Peer Reviewed / Open Access
• [Journal Article] A validation study of a consumer wearable sleep tracker compared to a portable EEG system in naturalistic conditions (2019)
  • Author(s): 1.Thomas Svensson, Ung-il Chung, Shinichi Tokuno, Mitsuteru Nakamura, Akiko Kishi Svensson
  • Journal Title: Journal of Psychosomatic Research Volume: 126 Pages: 109822
  • DOI: 10.1016/j.jpsychores.2019.109822
  • Peer Reviewed / Open Access
• [Presentation] Generalization performance improvement method using automatic feature selection in pathological voice detection. (2019)
  • Author(s): Kouta Suzuki, Shuji Shinohara, Masakazu Higuchi, Nobuhito Manome, Yasuhiro Omiya, Shunji Mitsuyoshi
  • Organizer: Neuroscience
  • Int'l Joint Research
• [Presentation] Parkinson’s disease detection from a small amount of data based on self-organizing maps. (2019)
  • Author(s): Nobuhito Manome, Shuji Shinohara, Kouta Suzuki, Yasuhiro Omiya, Masakazu Higuchi, Shunji Mitsuyoshi
  • Organizer: Neuroscience
  • Int'l Joint Research
• [Presentation] Pilot study of distinguish between dementia with Lewy bodies and healthy subjects using voice. (2019)
  • Author(s): Yasuhiro Omiya, Tomotaka Uraguchi, Takeshi Takano, Mitsuteru Nakamura, Shuji Shinohara, Masakazu Higuchi, Kouta Suzuki, Nobuhito Manome, Mitsuyoshi Ishida, Yorio Kumamoto, Shunji Mitsuyoshi, Shinichi Tokuno
  • Organizer: Neuroscience
  • Int'l Joint Research
• [Presentation] A Preliminary Study of Speech Emotion Recognition inside Automobile (2019)
  • Author(s): Kouta Suzuki, Naoki Hagiwara, Yasuhiro Omiya, Takashi Kirita, Shuji Shinohara, Nobuhito Manome, Shunji Mitsuyoshi
  • Organizer: The 21st International Conference on Human-Computer Interaction
  • Int'l Joint Research
• [Presentation] Detecting Persons with Major Depression by a Voice Index Based on the Relationship between Hurst Exponent and Zero Crossing Rate (2019)
  • Author(s): Shuji Shinohara, Hiroyuki Toda, Mitsuteru Nakamura, Yasuhiro Omiya, Masakazu Higuchi, Takeshi Takano, Nobuhito Manome, Kouta Suzuki, Taku Saito, Masaaki Tanichi, Shunji Mitsuyoshi, Tomotaka Uraguchi, Aihide Yoshino, Shinichi Tokuno
  • Organizer: The IEEE 41st International Engineering in Medicine and Biology Conference
  • Int'l Joint Research
• [Presentation] Identification of Parkinson’s Disease from Scarce Data Using Learning Vector Quantization (2019)
  • Author(s): Nobuhito Manome, Shuji Shinohara, Kouta Suzuki, Yasuhiro Omiya, Masakazu Higuchi, Shunji Mitsuyoshi
  • Organizer: The IEEE 41st International Engineering in Medicine and Biology Conference
  • Int'l Joint Research
• [Presentation] Parkinson’s Disease Detection Based on LightGBM (2019)
  • Author(s): Kouta Suzuki, Shuji Shinohara, Masakazu Higuchi, Nobuhito Manome, Yasuhiro Omiya, Shunji Mitsuyoshi
  • Organizer: The IEEE 41st International Engineering in Medicine and Biology Conference
  • Int'l Joint Research
• [Presentation] An Experiment to Detect Laryngomalacia Using Baby’s Crying Voice (2019)
  • Author(s): Yasuhiro Omiya, Mitsuteru Nakamura, Shuji Shinohara, Masakazu Higuchi, Kouta Suzuki, Nobuhito Manome, Shunji Mitsuyoshi, Isao Yamamoto, Susumu Mukai, Shinichi Tokuno
  • Organizer: The IEEE 41st International Engineering in Medicine and Biology Conference
  • Int'l Joint Research
• [Presentation] An Experiment to Distinguish Major Depression and Dementia with Lewy Bodies from Healthy Participants Using Voice (2019)
  • Author(s): Tomotaka Uraguchi, Yasuhiro Omiya, Shuji Shinohara, Kouta Suzuki, Nobuhito Manome, Yorio Kumamoto, Shinichi Tokuno
  • Organizer: The IEEE 41st International Engineering in Medicine and Biology Conference
  • Int'l Joint Research
• [Presentation] Effectiveness of Voice Biomarker in Detecting Bipolar Disorder (2019)
  • Author(s): Masakazu Higuchi, Mitsuteru Nakamura, Shuji Shinohara, Yasuhiro Omiya, Takeshi Takano, Kouta Suzuki, Nobuhito Manome, Hiroyuki Toda, Taku Saito, Aihide Yoshino, Shunji Mitsuyoshi, Shinichi Tokuno
  • Organizer: The IEEE 41st International Engineering in Medicine and Biology Conference
  • Int'l Joint Research
• [Presentation] SOM-based Algorithm for Multi-armed Bandit Problem (2019)
  • Author(s): Nobuhito Manome, Shuji Shinohara, Kouta Suzuki, Kosuke Tomonaga, Shunji Mitsuyoshi
  • Organizer: The IEEE International Joint Conference on Neural Networks
  • Int'l Joint Research
• [Presentation] Verification of the Ability to Identify Parkinson’s Disease Patients Using Learning Vector Quantization (2019)
  • Author(s): Nobuhito Manome, Shuji Shinohara, Kouta Suzuki, Kosuke Tomonaga, Shunji Mitsuyoshi
  • Organizer: Tthe 26th International Stress and Behavior Neuroscience and Biopsychiatry Conference
  • Int'l Joint Research
• [Presentation] A Voice Emotion Analysis of Fear based on Logistic Regression (2019)
  • Author(s): Wenqin Xu, Shuji Shinohara, Daijiro Harada, Reiko Kuroki, Shunji Mitsuyoshi
  • Organizer: The 26th International Stress and Behavior Neuroscience and Biopsychiatry Conference
  • Int'l Joint Research
• [Presentation] Emergence of Cooperative and Altruistic Behavior in SOM-based Agents (2019)
  • Author(s): Nobuhito Manome, Shuji Shinohara, Kouta Suzuki, Kosuke Tomonaga, Shunji Mitsuyoshi
  • Organizer: The 24th International Symposium on Artificial Life and Robotics 2019
  • Int'l Joint Research
• [Presentation] Relation between Stress Estimated by Voice Analysis and Blood Interleukin-1 Receptor Antagonist in High-Intensity Training (2019)
  • Author(s): Nakamura M, Suzuki G, Shinohara S, Omiya Y, Higuchi M, Takano T, Mitsuyoshi S, Kobayashi N, Tokuno S
  • Organizer: The IEEE 41st International Engineering in Medicine and Biology Conference
  • Int'l Joint Research
• [Presentation] Mind monitoring system (MIMOSYS) for mental and wellbeing of young students (2019)
  • Author(s): Popa D, Nechita F, Coman C, Barbu S, Shinohara S, Tokuno S, Nakamura M, Takano T
  • Organizer: X Simpósio Nacional de Investigação em Psicologia
  • Int'l Joint Research
• [Presentation] Evaluation of smart devices in IoT segment by using medical healthcare technology “MIMOSYS” (2019)
  • Author(s): Uraguchi T, Omiya Y, Takano T, Amemiya Y, Nakamura M, Takayama E, Tokuno S, Deguchi H
  • Organizer: The 12th Asian Control Conference
• [Presentation] Voice-Based Evaluation of Stress by Body Identification (2019)
  • Author(s): Higuchi M, Yamamoto I, Omiya Y, Nakamura M, Shinohara S, Takano T, Nakagawa K, Ohira H, Yamada Y, Hasegawa I, Mitsuyoshi S, Tokuno S
  • Organizer: 27th International "Stress and Behavior" Neuroscience and Biopsychiatry Conference
  • Int'l Joint Research
• [Presentation] Evaluation of Effect of Light Labor on Retired People Using Voice Analysis (2019)
  • Author(s): Nakamura M, Ikeuchi M, Oroguchi T, Yamanaka K, Amagi H, Shinohara S, Omiya Y, Higuchi M, Takano T, Mitsuyoshi S, Tokuno S
  • Organizer: 27th International "Stress and Behavior" Neuroscience and Biopsychiatry Conference
  • Int'l Joint Research
• [Presentation] Pilot study to detect Parkinson's disease based on vocal analysis (2019)
  • Author(s): Omiya Y, Nakamura M, Shinohara S, Higuchi M, Takano T, Mitsuyoshi S, Terashi H, Tokuno S
  • Organizer: 27th International "Stress and Behavior" Neuroscience and Biopsychiatry Conference
  • Int'l Joint Research
• [Presentation] Voice Analysis Opens the Door to the Future Health Society (2019)
  • Author(s): Nakamura M, Higuchi M, Shinohara S, Omiya Y, Takano T, Mitsuyoshi S, Tokuno S
  • Organizer: Nature創刊150周年記念シンポジウム 日本の科学の未来 持続可能な開発目標の達成に向けたビジョン
• [Presentation] Proposal of a voice disorder index for screening patients with Parkinson's disease(PWPD) (2019)
  • Author(s): Shinohara S, Terashi H, Omiya Y, Nakamura M, Higuchi M, Takano T, Uraguchi T, Mitsuyoshi S, Tokuno S
  • Organizer: The 14th International Conference on Alzheimer's and Parkinson's Diseases
  • Int'l Joint Research
• [Presentation] Feasibility Study for Estimation of Score of The Movement Disorder Society Unified Parkinson’s Disease Rating Scale Part III Using Voice (2019)
  • Author(s): Nakamura M, Shinohara S, Higuchi M, Omiya Y, Takano T, Mitsuyoshi S, Terashi H, Mitoma H, Tokuno S
  • Organizer: The 14th International Conference on Alzheimer's and Parkinson's Diseases
  • Int'l Joint Research
• [Presentation] Pilot study to detect Alzheimer’s disease based on vocal analysis (2019)
  • Author(s): Omiya Y, Nakamura M, Shinohara S, Higuchi M, Takano T, Uraguchi T, Mitsuyoshi S, Ishida M, Sanjo S, Tokuno S
  • Organizer: The 14th International Conference on Alzheimer's and Parkinson's Diseases
  • Int'l Joint Research
• [Presentation] ハースト指数ゼロロ交差率に基つく音声指標によるうつ重症度測定 (2019)
  • Author(s): 篠原 修二, 戸田 裕之, 中村 光晃, 大宮 康宏, 樋口 政和, 高野 毅, 斎藤 拓, 谷知 正章, 光吉 俊二, 吉野 相英, 徳野 慎一
  • Organizer: 第58回日本生体医工学会
• [Presentation] 学習ベクトル量子化を用いた少数データからのパーキンソン病患者の識別. (2019)
  • Author(s): 馬目 信人, 篠原 修二, 鈴木 康大, 朝長 康介, 光吉 俊二
  • Organizer: 第58回日本生体医工学会
• [Presentation] 音声分析に基づくアルツハイマー型認知症の検出のための検討 (2019)
  • Author(s): 大宮 康宏, 中村 光晃, 篠原 修二, 樋口 政和, 髙野 毅, 浦口 智貴, 光吉 俊二, 三條 信夫, 徳野 慎一
  • Organizer: 第58回日本生体医工学会
• [Presentation] 体位に依存した音声特徴量の変化に基づく閉塞性睡眠時無呼吸リスク推測手法の高精度化に関する検討 (2019)
  • Author(s): 中村 光晃, 大宮 康宏, 篠原 修二, 樋口 政和, 高野 毅, 光吉 俊二, 淡野 宏輔, 田中 俊一, 徳野 慎一
  • Organizer: 第58回日本生体医工学会
• [Presentation] 音声によるパーキンソン病患者の重症度判別 (2019)
  • Author(s): 樋口 政和, 中村 光晃, 篠原 修二, 大宮 康宏, 高野 毅, 赫 寛雄, 三苫 博, 光吉 俊二, 徳野 慎一
  • Organizer: 第58回日本生体医工学会
• [Presentation] 自己組織化マップを用いた定常・非定常環境に適応可能な多腕バンディットアルゴリズム (2019)
  • Author(s): 馬目 信人, 篠原 修二, 鈴木 康大, 朝長 康介, 光吉 俊二
  • Organizer: 第33回人工知能学会全国大会
• [Presentation] 機械学習を用いた構音障害分類における音声特徴量間の耐ノイズ性能の比較 (2019)
  • Author(s): 鈴木 康大, 篠原 修二, 馬目 信人, 朝長 康介, 光吉 俊二
  • Organizer: 第33回人工知能学会全国大会
• [Presentation] SOMに基づく多腕バンディットアルゴリズム (2019)
  • Author(s): 馬目 信人, 篠原 修二, 鈴木 康大, 朝長 康介, 光吉 俊二
  • Organizer: 第81回情報処理学会全国大会