Development of cerebral activity examination that is simple and robust against repetition by using wearable NIRS

2018 Fiscal Year Final Research Report

• Project/Area Number: 16K01497
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Rehabilitation science/Welfare engineering
• Research Institution: Gunma University
• Principal Investigator: Kikuchi Senichiro 群馬大学, 大学院保健学研究科, 教授 (60323341)
• Co-Investigator(Kenkyū-buntansha): 福田 正人 群馬大学, 大学院医学系研究科, 教授 (20221533) ; 服部 卓 群馬大学, 医学部附属病院, 助教 (30241897)
• Project Period (FY): 2016-04-01 – 2019-03-31
• Keywords: 馴化 / 脳機能計測 / 反復計測 / ＮＩＲＳ

Outline of Final Research Achievements

The monitoring of cerebral activity during long-term therapy of psychiatry is useful for the development of new protocols and assessments of the therapy. For clinical use, the authors tried to develop an examination by using a wearable Near infra-red Spectroscopy (NIRS) device with a neurocognitive task that is robust against repetition (habituation). Participants were fourteen healthy university students. We used a WOT-100, ten channel wearable NIRS device. Each participant underwent three tasks (deceitful reverse rock paper scissors, Stroop test, animal Stroop test) on a zero day, one week after, two weeks after, and three weeks after. Then the integral values of the oxyhemoglobin during the task were calculated. Stroop task was the only task with no habituation. We concluded that the Stroop task was the most favorable of the three.

Free Research Field

臨床精神医学、認知神経科学

Academic Significance and Societal Importance of the Research Achievements

従来、ＮＩＲＳ検査の刺激課題として、様々な課題が検討されてきたが、反復計測に強い、すなわち複数の課題を用いて馴化の少ない課題を求めた研究はきわめて少ない。本研究により、認知か台の選択による馴化の仕組みにつき、一部解明が行われた。今後文字Stroop不一致課題を中心とした課題の採用が望ましいという根拠が得られたところに意義があると思われる。