Effect of molecular mechanism on the interaction between Exercise capasity and intestinal environment

2019 Fiscal Year Final Research Report

• Project/Area Number: 16K01600
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Developmental mechanisms and the body works
• Research Institution: Yamagata Prefectural Yonezawa University of Nutrition Sciences
• Principal Investigator: Kato Morimasa 山形県立米沢栄養大学, 健康栄養学部, 教授 (20399330)
• Project Period (FY): 2016-04-01 – 2020-03-31
• Keywords: レジスタンストレーニング / 腸内環境

Outline of Final Research Achievements

This study examined the effect of resistance training on the intestinal environment.　Fourteen healthy females underwent resistance training for 8 weeks and detraining for 8 weeks, and examined the effects on exercise capacity and intestinal environment. After 8 weeks of resistance training, muscle mass and strength showed a significant increase, and after detraining, these significant differences disappeared. Muscular mass showed changes associated with Coprobacillus in gut microbiome and anserine and asparagine in fecal metabolites. Furthermore, detraining showed significant changes in fecal amino acid metabolites.The changes in body composition due to resistance training, has been suggested that also related to differences in gut microbiota.

Free Research Field

運動生理学

Academic Significance and Societal Importance of the Research Achievements

研究より腸内環境は運動の影響も受ける可能性が示唆された。縦断的研究から運動の影響を見た知見は少なく、レジスタンストレーニングで腸内環境の特性が見えてきた意義は大きい。この知見ベースに、効率的なレジスタンストレーニングやサプリメント、さらには加齢に伴う筋委縮抑制の運動について応用することが期待される。