2018 Fiscal Year Final Research Report
Intensity-interferometric optical coherence tomography with wavefront shaping for deep imaging
Project/Area Number |
16K04990
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Optical engineering, Photon science
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Research Institution | National Institute of Advanced Industrial Science and Technology |
Principal Investigator |
SHIRAI Tomohiro 国立研究開発法人産業技術総合研究所, 計量標準総合センター, 上級主任研究員 (20357239)
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Research Collaborator |
FRIBERG Ari T.
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Project Period (FY) |
2016-04-01 – 2019-03-31
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Keywords | コヒーレンス理論 / 強度干渉法 / イメージング / 光コヒーレンストモグラフィ(OCT) / 量子OCT / 波面制御 / 生体光計測 |
Outline of Final Research Achievements |
A practical and reliable method of realizing dispersion-insensitive high-resolution optical coherence tomography (OCT) based on intensity interferometry was devised and a recipe was developed for reducing unavoidable multiple artifacts simultaneously. They were implemented experimentally to prove that the intensity-interferometric OCT in question is highly promising as a practical tool for cross-sectional imaging. Furthermore, the wavefront shaping technique for controlling the multiple scattering light was improved and then combined with the intensity-interferometric OCT. As a result, it was found experimentally that high-resolution deeper cross-sectional imaging through scattering media is possible by means of the intensity-interferometric OCT with wavefront shaping.
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Free Research Field |
物理光学,統計光学,応用光学
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Academic Significance and Societal Importance of the Research Achievements |
光によるイメージング技術は、医療分野では、各種疾患の低侵襲かつ早期診断を可能にする新しい診断機器の原理になるなど、人々の生活に密着した広範な分野において重要な役割を果たしている。しかし、光を使って生体組織の深部(数ミリメートル程度以上)を高分解能(細胞が識別できる程度)でイメージングする技術は未だ確立していない。本研究の成果は、光を使って生体組織などの多重散乱媒質内部をより深くより高精度に断層イメージングする技術の発展に大いに貢献するものと期待される。
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