2018 Fiscal Year Final Research Report
Longitudinal epidemiological studies to clarify the difference in effectiveness of countermeasures against influenza in different age groups.
| Project/Area Number |
16K09052
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Epidemiology and preventive medicine
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| Research Institution | Gunma University (2017-2018)
Shinshu University (2016) |
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Principal Investigator |
Mitsuo Uchida 群馬大学, 大学院医学系研究科, 准教授 (00377251)
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| Research Collaborator |
Kawa Shigeyuki
Kaneko Minoru
Honda Takayuki
Yamamoto Hiroshi
Hidaka Yoshihiko
Takeuchi Shouhei
Saito Masaya
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| Project Period (FY) |
2016-04-01 – 2019-03-31
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| Keywords | インフルエンザ / 疫学 / 小学生 / 中学生 / ワクチン / 質問紙 |
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| Outline of Final Research Achievements |
In this study, differences in epidemic dynamics and symptoms of seasonal influenza were evaluated by epidemiological methods in elementary school and junior high school students. Influenza information was obtained from the questionnaire for guardians of 7867 children at 17 elementary and junior high schools from 2016 to 2017. The cumulative incidence rate was higher in elementary school children than in junior high school students (22.5% vs 18.1%), but the reproduction number, which is an index of epidemic dynamics, was similar (1.13 vs 1.10). The proportion of pain symptoms was higher in junior high school students, but fever duration was longer in elementary schoolchildren. As a result of this study, in both elementary and junior high school students, higher grade, regular going out, and vaccination had contributed to suppression of influenza symptom onset.
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| Free Research Field |
感染症の疫学
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| Academic Significance and Societal Importance of the Research Achievements |
わが国では，学校組織において毎年インフルエンザの流行を認めるが，現在のところ完全に制御する方法は確立できていない。これは学校現場においてインフルエンザの流行動態や感染対策の効果が不明瞭であることが原因として挙げられる。また臨床現場で年齢別にインフルエンザの発症割合やワクチンの感受性は異なることが指摘されているが，学校現場では不明瞭である。本研究は，小中学生におけるインフルエンザの流行動態はほとんど差を認めないこと，また症状に差があることを明らかにした。本研究成果は，今後学校現場におけるインフルエンザの拡大様式を明らかにするための情報として有用であると考えられる。
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