Measurements of vagal nerve activity by using in vivo two-photon imaging and MEMS electric recording

2017 Fiscal Year Final Research Report

• Project/Area Number: 16K12889
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Biomedical engineering/Biomaterial science and engineering
• Research Institution: National Cardiovascular Center Research Institute
• Principal Investigator: Kamiya Atsunori 国立研究開発法人国立循環器病研究センター, 研究所, 循環モデル解析研究室長 (30324370)
• Co-Investigator(Renkei-kenkyūsha): SUGIMACHI MASARU 国立研究開発法人国立循環器病センター研究所, 部長 (40250261) ; KAZUTO KOBAYASHI 公立大学法人福島県立医科大学, 生体情報伝達研究所生体機能研究部門, 教授 (90211903)
• Project Period (FY): 2016-04-01 – 2018-03-31
• Keywords: 自律神経

Outline of Final Research Achievements

Autonomic nervous system senses various biosignal by afferent (sensory) nerve fibers locating at whole body and regulate individual organs by efferent nerve fibers, and thus is one of key mechanisms that organize multiple organs functionally and maintain homeostasis (i.e., circulation, respiration, energy metabolism, thermoregulation) and life. However, because of less-developed technology for measurement of nerve activity, autonomic nerve activity is unclear except limited organs and nerve-types. In this study, we have recorded vagal nerve activity that has been known as difficult to be measured, and also did intra-organ vagal nerve activity that has never been measured.

Free Research Field

複合領域