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2017 Fiscal Year Final Research Report

Brain circuit for happy emotion

Research Project

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Project/Area Number 16K13112
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Basic / Social brain science
Research InstitutionKagoshima University

Principal Investigator

KUWAKI Tomoyuki  鹿児島大学, 医歯学域医学系, 教授 (80205260)

Co-Investigator(Renkei-kenkyūsha) YAMANAKA Akihiro  名古屋大学, 環境医学研究所, 教授 (60323292)
Research Collaborator LI Zhi  
ISOMICHI Takuto  
YAMASHITA Akira  
OOTSUKA Youichirou  
KASHIWADANI Hideki  
MIYATA Kohei  
TASHIRO Shogo  
YAMAGUCHI Ran  
ISHIKAWA Sodemi  
SAKURAI Takeshi  
KAJIYA Katsuko  
KANMURA Yuichi  
FUTATSUKI Takahiro  
Khairunnisa Novita Ikbar  
ARITA Kazunori  
KAKIHANA Yasuyuki  
Project Period (FY) 2016-04-01 – 2018-03-31
Keywords感性・情動・感情 / オレキシン / 情動脱力発作 / 快情動 / 神経科学
Outline of Final Research Achievements

Happy emotion is believed to be beneficial for protection of disease and promotion of health. The aim of this study was to get biological evidence for the empirical knowledge by revealing neural circuit supporting for the phenomenon. We supposed that cataplexy attack in narcolepsy animal might be an objective measure of the subjective happy emotion because cataplexy is triggered by happy emotion at least in humans. Using narcolepsy model mice, we systematically searched for the brain region that was activated during or just after the cataplexy attack. We found that the accumbens nucleus was the most activated brain site. Next step will be the examination of possible relationship between activity of the accumbens nucleus and health promotion.

Free Research Field

脳科学

URL: 

Published: 2019-03-29  

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