Identifying and fabricating active sites for calcium phosphate nucleation on ultra-thin SiO2 film on TiO2 substrate

2017 Fiscal Year Final Research Report

• Project/Area Number: 16K13624
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Nanomaterials chemistry
• Research Institution: Kobe University
• Principal Investigator: Sasahara Akira 神戸大学, 理学研究科, 学術研究員 (40321905)
• Project Period (FY): 2016-04-01 – 2018-03-31
• Keywords: リン酸カルシウム / チタン / インプラント / 酸化チタン

Outline of Final Research Achievements

The calcium phosphate (CP) formation on titanium dioxide (TiO2) is the key process to control the performance of the Ti implants. The formation of CP in simulated body fluid (Hank's buffered salt solution, HBSS)) was examined on the rutile TiO2(110) surface.
TiO2(110)-(1×1) surfaces prepared in ultrahigh vacuum (UHV) was inert to the formation of CP. Phosphate ions are adsorbed on the (1×1) surface to form a monolayer with the (2×1) periodicity. The (2×1) periodicity does not match the arrangement of the phosphate ions in the dicalcium phosphate dihydrate (CaHPO4·2H2O). Whereas, CP was formed on TiO2(110) surfaces annealed in air. When the air-annealed surface was subsequently annealed in O2, the surface top layer transformed to amorphous to rutile structure. The O2-annealed surface with the (1×1) structure was inert to the formation of the CP. The results demonstrated that the formation of CP on TiO2 is sensitive to the surface nanostructures.

Free Research Field

表面科学