Development of Nanospace-Controlled Catalysis towards Challenging Transformation of Saturated Hydrocarbons

2017 Fiscal Year Final Research Report

• Project/Area Number: 16K13988
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Synthetic chemistry
• Research Institution: Hokkaido University
• Principal Investigator: Iwai Tomohiro 北海道大学, 理学研究院, 助教 (30610729)
• Project Period (FY): 2016-04-01 – 2018-03-31
• Keywords: 遷移金属錯体触媒 / 配位子設計 / 白金 / 金 / ビスホスフィン / ピンサー配位子

Outline of Final Research Achievements

The development of nanospace-controlled catalysis towards challenging molecular transformations, focusing on direct functionalization of saturated hydrocarbons, was carried out. Cationic gold(I) complexes with hollow-shaped triethynylphosphine ligands efficiently catalyzed intramolecular [2+2] cycloaddition of 1,9-enynes to afford cyclobutene-fused eight-membered carbocycles. For construction of precise catalytic environments, bulky P-alkynyl-substituted bisphosphine and PCP-pincer-type ligands were designed and synthesized. These polydentate ligands were applied to Pt(II)-catalyzed cycloisomerization of 1,8-enynes.

Free Research Field

有機合成化学