Synthesis of Telechelic Polymers with Secondary-Structure-Controlled Main Chains Leading to the Construction of Unprecedented Structures

2017 Fiscal Year Final Research Report

• Project/Area Number: 16K14011
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Polymer chemistry
• Research Institution: Kansai University
• Principal Investigator: Sanda Fumio 関西大学, 化学生命工学部, 教授 (70262318)
• Research Collaborator: MIYAGI Yu ら関西大学, 大学院理工学研究科, 大学院生 ; TAKAOKA Shinya ら関西大学, 大学院理工学研究科, 大学院生 ; KAMADA Takeru ら関西大学, 大学院理工学研究科, 大学院生
• Project Period (FY): 2016-04-01 – 2018-03-31
• Keywords: テレケリックポリマー / らせん共役高分子 / 末端構造制御 / 蛍光発光 / ペプチド / 水素結合 / 薗頭-萩原カップリング / コンホメーション制御

Outline of Final Research Achievements

(1)A novel polymer consisting of helical peptide and phenyleneethynylene moiety was synthesized by the self Sonogashira coupling polymerization of a telechelic helical peptide. The peptide with modified terminal groups exhibited Cotton effects higher than those of the precursor, presumably due to the participation of the terminal amide groups into the intramolecular hydrogen bonding strands as well as increase of rigidity due to the formation of conjugated phenyleneethynylene moieties, resulting in the stabilization of the helical structure.
(2)Telechelic helical poly(phenyleneethynylene)s bearing end iodo and ethynyl groups were successfully synthesized by the Sonogashira coupling reaction of the prepolymer with N-Boc-3,5-diiodo-4-hydroxy-D-phenylglycine hexylamide and p-diethynylbenzene, respectively. The formed polymer was treated by Sonogashira coupling polymerization with 1,6-diethynylpyrene and 4,4-diethynylbiphenyl to obtain the corresponding polymers.

Free Research Field

高分子合成