2017 Fiscal Year Final Research Report
African killifish discloses Parkinson-like phenotypes during aging.
| Project/Area Number |
16K14597
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Laboratory animal science
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| Research Institution | Niigata University |
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Principal Investigator |
Matsui Hideaki 新潟大学, 研究推進機構, 准教授 (60710853)
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| Project Period (FY) |
2016-04-01 – 2018-03-31
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| Keywords | パーキンソン病 |
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| Outline of Final Research Achievements |
Short-lived african killifish disclosed Parkinson-like phenotypes during aging. By utilizing this fish, we showed that propagation of alpha-synuclein of this fish. Dissection of the nervous system or depletion of alpha-synuclein ameliorated Parkinson-like neurodegeneration in this fish.
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| Free Research Field |
神経科学
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