2017 Fiscal Year Final Research Report
Signal transduction in cell is only one way?
| Project/Area Number |
16K14710
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Biophysics
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| Research Institution | Osaka University |
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Principal Investigator |
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| Project Period (FY) |
2016-04-01 – 2018-03-31
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| Keywords | バクテリア |
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| Outline of Final Research Achievements |
E.coli recognize the environmental stimuli by receptor patch at cell pole and phosphorylate CheA, CheA-P transfer to CheY, CheY-P bind to flagellar motor and rotational direction changed from CCW to CW. In this study, we validate a feedbacksystem of signal transduction system in cell. When the rotation of one motor on the cell was stopped, CWbias of another motor on the same cell was gradually increased. This result suggested that the stopped motor activated the CheA and increased the CWbias of other motor on the same cell.
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| Free Research Field |
生物物理学
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