Starting up the functional ribosome-omics (ribosomomics): an approach from the translation arrest

2017 Fiscal Year Final Research Report

• Project/Area Number: 16K14746
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Plant molecular biology/Plant physiology
• Research Institution: Hokkaido University
• Principal Investigator: NAITO Satoshi 北海道大学, 農学研究院, 教授 (20164105)
• Research Collaborator: TAKAMATSU Seidai ; MIURA Yuka
• Project Period (FY): 2016-04-01 – 2018-03-31
• Keywords: リボソーム / 多様性 / ストレス応答

Outline of Final Research Achievements

In Arabidopsis, ribosomal protein genes are consisted of two to four paralogs, and, in most of the cases, the difference in the encoded amino acid sequences is one to several percent from each other. The possibility that these differences are plants’ strategy to cope with the changing environmental conditions was explored by analyzing ribosome stalling under specific condition as well as analysis of published transcriptome data. The latter analysis showed that expression levels of paralogous genes change depending on the stress conditions. Whether the paralogous subunit proteins are functioning in the ribosome particles is yet to be studied.

Free Research Field

分子生物学