Studies on estimation method of key transcription factors by bioinformatics

2017 Fiscal Year Final Research Report

• Project/Area Number: 16K14857
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Horticultural science
• Research Institution: National Agriculture and Food Research Organization
• Principal Investigator: FUJII Hiroshi 国立研究開発法人農業・食品産業技術総合研究機構, 果樹茶業研究部門, 主席研究員 (00355398)
• Project Period (FY): 2016-04-01 – 2018-03-31
• Keywords: 遺伝子ネットワーク / 代謝制御 / 転写因子 / マイクロアレイ / カロテノイド / カンキツ

Outline of Final Research Achievements

A number of transcription factors are involved in the expression control of carotenoid metabolism enzyme genes. Understanding of the relationship of the transcription factor is important to identify key genes of control of metabolism and metabolism design toward component breeding. Using carotenoid metabolism as a model, gene network was configured. The gene network was comprised of carotenoid metabolism genes and transcription factors by SiGN-BN software that estimate directed gene network. The genes located in the uppermost stream were estimated as the key genes of metabolism control.

Free Research Field

バイオインフォマティクス