Finding of silkworm monosony-why the monosomy survive-

2017 Fiscal Year Final Research Report

• Project/Area Number: 16K15064
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Insect science
• Research Institution: Iwate University
• Principal Investigator: Sahara Ken 岩手大学, 農学部, 教授 (30241368)
• Co-Investigator(Kenkyū-buntansha): 金児 雄 弘前大学, 農学生命科学部, 助教 (90633610)
• Project Period (FY): 2016-04-01 – 2018-03-31
• Keywords: モノソミー / カイコ / 第2染色体 / FISH

Outline of Final Research Achievements

We find monosomy silkworm individuals which are reproducible and have both female and males. By crossing two mutant strains with the monosomy individuals we developed monosomy strain that can be discriminated by the visible phenotypes. RNAseq revealed that the expression of 2nd chromosome genes in the monosomy progenies seems to be about half amount that in the normal. Hence we concluded dosage compensation for the autosome gene cannot be functioned in the silkworms.

Free Research Field

昆虫細胞遺伝学